Oral remdesivir derivative VV116 is a potent inhibitor of respiratory syncytial virus with efficacy in mouse model

  • Signal Transduct Target Ther. 2022 Apr 16;7(1):123. doi: 10.1038/s41392-022-00963-7.
Ruxue Zhang   #  1  2 ,  Yumin Zhang   #  1 ,  Wei Zheng   #  2  3 ,  Weijuan Shang  1 ,  Yan Wu  1 ,  Ning Li  4 ,  Jun Xiong  4 ,  Hualiang Jiang  2  3 ,  Jingshan Shen  2  3 ,  Gengfu Xiao  1  2 ,  Yuanchao Xie  5  6 ,  Leike Zhang  7  8
Affiliations
  • 1. State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China.
  • 2. University of Chinese Academy of Sciences, Beijing, 100049, China.
  • 3. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • 4. Shanghai Junshi Biosciences Co., Ltd., Shanghai, 200126, China.
  • 5. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. [email protected].
  • 6. Lingang Laboratory, Shanghai, 200031, China. [email protected].
  • 7. State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China. [email protected].
  • 8. University of Chinese Academy of Sciences, Beijing, 100049, China. [email protected].
  • # Contributed equally.
PMID: 35429988 DOI: 10.1038/s41392-022-00963-7
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