Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy

  • Signal Transduct Target Ther. 2023 Dec 15;8(1):454. doi: 10.1038/s41392-023-01715-x.
Lei Yu  #  1 ,  Pengcheng Zhao  #  1 ,  Yaoliang Sun  #  2 ,  Zening Zheng  #  1 ,  Wenhao Du  2 ,  Lishan Zhang  2 ,  Yaxu Li  1 ,  Longyan Xie  1 ,  Shilin Xu  3 ,  Ping Wang  4
Affiliations
  • 1. Tongji University Cancer Center, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
  • 2. Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • 3. Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. [email protected].
  • 4. Tongji University Cancer Center, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China. [email protected].
  • # Contributed equally.
PMID: 38097557 DOI: 10.1038/s41392-023-01715-x
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