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QP5020

QP5020 (compound 28) is an inhibitor of QPCTL with an IC⁵⁰ value of 15 nM. QP5020 has antitumor efficacy.

For research use only. We do not sell to patients.

CAS No.: 3027434-06-3
Formula: C₂₀H₁₉FN₆
Molecular Weight:362.40

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

QP5020 Chemical Structure

CAS No.: 3027434-06-3

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Sample (0.1mg)

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

QP5020 (compound 28) is an inhibitor of QPCTL with an IC⁵⁰ value of 15 nM. QP5020 has antitumor efficacy^[1].

Chemical Information

CAS No. 3027434-06-3
Molecular Weight 362.40
Formula C₂₀H₁₉FN₆
SMILES

N#CC1=CC=CC(C2=CC=C(F)N=C2)=C1N3CCC(C4=NN=CN4C)CC3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lei Yu, et al. Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy. Signal Transduct Target Ther. 2023, 8, 1. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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