EGFR molecular degraders: preclinical successes and the road ahead

  • Future Med Chem. 2025 Mar;17(6):633-636. doi: 10.1080/17568919.2025.2463871.
Naveen Chand Rallabandi  1 ,  Dayanand Panpatil  1  2 ,  Digvijay Gahtory  3 ,  Umashanker Navik  4 ,  Raj Kumar  1
Affiliations
  • 1. Department of Pharmaceutical Sciences and Natural Products, Central university of Punjab, Bathinda, India.
  • 2. Department of Medicinal Chemistry, Integral Biosciences, Noida, India.
  • 3. BIMINI Biotech, Leiden, Netherlands.
  • 4. Department of Pharmacology, Central University of Punjab, Bathinda, India.
PMID: 39928493 DOI: 10.1080/17568919.2025.2463871
Keywords
EGFR; EGFR degraders; PROTACs; mutant EGFR; preclinical studies; targeted protein degradation.
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