TRIB1 silencing attenuates epilepsy by restoring mitochondrial homeostasis and suppressing microglia-driven neuroinflammation via MAPK pathway inhibition

  • J Mol Histol. 2025 Sep 5;56(5):295. doi: 10.1007/s10735-025-10580-7.
Chunying Liao  1 ,  Jie Cao  1 ,  Hanyi Zeng  1 ,  Cuiyin Chen  1 ,  Jianqing Yuan  2
Affiliations
  • 1. Department of Neurology, The First Affiliated Hospital of Gannan Medical University, No.128, Jinling Road, Zhanggong District, Ganzhou, 341000, Jiangxi, China.
  • 2. Department of Neurology, The First Affiliated Hospital of Gannan Medical University, No.128, Jinling Road, Zhanggong District, Ganzhou, 341000, Jiangxi, China. [email protected].
PMID: 40908404 DOI: 10.1007/s10735-025-10580-7
Keywords
Epilepsy; Hub genes; Mitogen-activated protein kinase (MAPK) signaling pathway; Tribbles homolog 1 (TRIB1).
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