Ethanol extract of Vanilla planifolia stem induces autophagy and alters transcriptome networks in pancreatic ductal adenocarcinoma cells

  • Gene. 2026 Sep 20:1005:150258. doi: 10.1016/j.gene.2026.150258.
Hui Hua Chang  1 ,  Ting-Yu Lin  2 ,  Chih-Ning Hsu  2 ,  I-Ning Yang  3 ,  Yuan-Shuo Hsueh  4
Affiliations
  • 1. Institute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan; School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Department of Pharmacy, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Department of Pharmacy, National Cheng Kung University Hospital, Dou-Liou Branch, Yunlin, Taiwan.
  • 2. Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
  • 3. Institute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Division of Nephrology, Department of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan; Department of Pharmaceutical Science and Technology, Chung Hwa University of Medical Technology, Tainan, Taiwan.
  • 4. Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Physiology, School of Post Baccalaureate Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Center for Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. Electronic address: [email protected].
PMID: 42242329 DOI: 10.1016/j.gene.2026.150258
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