Cytotoxic aromatic triterpenes from Maytenus ilicifolia and Maytenus chuchuhuasca

  • J Nat Prod. 1994 Dec;57(12):1675-81. doi: 10.1021/np50114a009.
O Shirota  1 ,  H Morita ,  K Takeya ,  H Itokawa
Affiliations
  • 1. Department of Pharmacognosy, Tokyo College of Pharmacy, Japan.
PMID: 7714534 DOI: 10.1021/np50114a009
Abstract

The isolation and structure elucidation of four cytotoxic aromatic Triterpenes [1-4] along with three known quinoid Triterpenes [5-7] from the South American medicinal Plants Maytenus ilicifolia and M. chuchuhuasca are described. The structures of these aromatic Triterpenes contained aromatized A rings and C-6 oxygenated B rings, and were elucidated by 1H- and 13C-nmr spectroscopic studies and by X-ray crystallographic analysis of 3.