Two new lignans with activity against influenza virus from the medicinal plant Rhinacanthus nasutus

  • J Nat Prod. 1997 Jun;60(6):635-7. doi: 10.1021/np960613i.
M R Kernan  1 ,  A Sendl ,  J L Chen ,  S D Jolad ,  P Blanc ,  J T Murphy ,  C A Stoddart ,  W Nanakorn ,  M J Balick ,  E J Rozhon
Affiliations
  • 1. Shaman Pharmaceuticals, South San Francisco, California 94080-4812, USA. [email protected]
PMID: 9214738 DOI: 10.1021/np960613i
Abstract

Two new Lignans, rhinacanthin E (1) and rhinacanthin F (2), were isolated from the aerial parts of the plant Rhinacanthus nasutus. Their structures were established by detailed spectroscopic analysis. These compounds show significant Antiviral activity against Influenza Virus type A.