Q94 hydrochloride

Q94 hydrochloride, a selective PAR1 antagonist (IC50=916 nM), can selectively block PAR1/Gαq interaction and signalling. Q94 hydrochloride blocks PAR1-mediated increases in both CCL2 mRNA and protein levels in a dose-dependent manner. Q94 hydrochloride also completely blocks thrombin-induced ERK1/2 and MLC phosphorylation.

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  • CAS. Nr.: 1052076-77-3
  • Formel: C21H18Cl2N2
  • Molecular Weight:369.29
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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