2. Epigenetics
  3. MicroRNA
  4. Remlarsen

Remlarsen (MRG-201), a miR-29b mimic, acts a miR-29b agonist. Remlarsen has the potential for preventiong formation of a fibrotic scar or cutaneous fibrosis.

For research use only. We do not sell to patients.

RNA, (Am-Am-Cm-A-Cm-Um-G-Um-Um-Um-A-Cm-A-A-A-Um-G-G-Um-Cm-Cm-Um-A), 3′-[3-[[6-[(3β)-cholest-5-en-3-yloxy]hexyl]oxy]-2-hydroxypropyl hydrogen phosphate], complex with RNA ((2′-deoxy-2′-fluoro)U-A-G-(2′-deoxy-2′-fluoro)C-A-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)C-A-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-G-A-A-A-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)C-A-G-(2′-deoxy-2′-fluoro)U-G-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-sp-U-sp-U) (1:1)

Remlarsen Chemical Structure

CAS No. : 1848266-71-6

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Based on 1 publication(s) in Google Scholar

Remlarsen Related Antibodies

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Description

Remlarsen (MRG-201), a miR-29b mimic, acts a miR-29b agonist. Remlarsen has the potential for preventiong formation of a fibrotic scar or cutaneous fibrosis[1].

In Vitro

Remlarsen (MRG-201) is active in regulating PD biomarker expression in the skin[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Remlarsen Related Antibodies
Clinical Trial
Molecular Weight

16059.5 (AS: 7961.8; SS: 8097.7)

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

RNA, (Am-Am-Cm-A-Cm-Um-G-Um-Um-Um-A-Cm-A-A-A-Um-G-G-Um-Cm-Cm-Um-A), 3′-[3-[[6-[(3β)-cholest-5-en-3-yloxy]hexyl]oxy]-2-hydroxypropyl hydrogen phosphate], complex with RNA ((2′-deoxy-2′-fluoro)U-A-G-(2′-deoxy-2′-fluoro)C-A-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)C-A-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-G-A-A-A-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)C-A-G-(2′-deoxy-2′-fluoro)U-G-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-sp-U-sp-U) (1:1)
SMILES

[Remlarsen]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (Need ultrasonic)

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Purity & Documentation
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Remlarsen Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Remlarsen1848266-71-6MRG-201MRG201MRG 201MicroRNAmiRNAmiR-29bmimicfibroticscarcutaneousInhibitorinhibitorinhibit

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