Remlarsen
Based on 1 Customer Validation
Remlarsen (MRG-201), a miR-29b mimic, acts a miR-29b agonist. Remlarsen has the potential for preventiong formation of a fibrotic scar or cutaneous fibrosis.
For research use only. We do not sell to patients.
- CAS No.: 1848266-71-6
- Molecular Weight:16059.5 (AS: 7961.8; SS: 8097.7)
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Remlarsen (MRG-201) is active in regulating PD biomarker expression in the skin[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1848266-71-6
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Appearance Solid
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Molecular Weight 16059.5 (AS: 7961.8; SS: 8097.7)
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Color White to off-white
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SMILES
[Remlarsen]
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Synonyms
MRG-201
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Sequence
RNA, (Am-Am-Cm-A-Cm-Um-G-Um-Um-Um-A-Cm-A-A-A-Um-G-G-Um-Cm-Cm-Um-A), 3′-[3-[[6-[(3β)-cholest-5-en-3-yloxy]hexyl]oxy]-2-hydroxypropyl hydrogen phosphate], complex with RNA ((2′-deoxy-2′-fluoro)U-A-G-(2′-deoxy-2′-fluoro)C-A-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)C-A-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-G-A-A-A-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)C-A-G-(2′-deoxy-2′-fluoro)U-G-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-sp-U-sp-U) (1:1)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 100 mg/mL (Need ultrasonic)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)