Resmethrin-d6-1
Resmethrin-d6-1 (Benzofuroline-d6-1) is the deuterated-labeled Resmethrin (HY-114558). Resmethrin (Benzofuroline) is a reproductively toxic compound that inhibits spermatogenesis and induces apoptosis of germ cells in mouse testis culture in vitro, but has no significant toxicity to supporting cells and interstitial cells.
For research use only. We do not sell to patients.
- Formula: C22H20D6O3
- Molecular Weight:344.48
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 10453-86-8
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Appearance Solid
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Molecular Weight 344.48
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Formula C22H20D6O3
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Color White to off-white
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SMILES
O=C(C1C(C)(C)C1/C=C(C)/C)OCC2=COC(CC3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])=C2[2H]
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Synonyms
Benzofuroline-d6-1; Isathrine-d6-1; Resmethrin-d6-1 (mixture of isomers)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (597 KB)
- English - EN (597 KB)
- Français - FR (597 KB)
- Deutsch - DE (597 KB)
- Norwegian - NO (597 KB)
- Español - ES (597 KB)
- Swedish - SV (597 KB)
- Italian - IT (597 KB)
- Korean - KR (597 KB)
- Portuguese - PT (597 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)