1. Apoptosis
  2. RIP kinase
  3. RIPK-IN-4

RIPK-IN-4 

Cat. No.: HY-107978 Purity: 99.35%
Handling Instructions

RIPK-IN-4 is a potent and selective RIPK2 inhibitor with excellent oral bioavailability, and has an IC50 of 3 nM.

For research use only. We do not sell to patients.

RIPK-IN-4 Chemical Structure

RIPK-IN-4 Chemical Structure

CAS No. : 2141969-56-2

Size Price Stock Quantity
5 mg USD 450 In-stock
Estimated Time of Arrival: December 31
10 mg USD 750 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2250 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

RIPK-IN-4 is a potent and selective RIPK2 inhibitor with excellent oral bioavailability, and has an IC50 of 3 nM[1].

IC50 & Target

IC50: 3 nM (RIPK2)[1]

Molecular Weight

392.45

Formula

C₁₈H₂₁FN₄O₃S

CAS No.

2141969-56-2

SMILES

O=S(C1=CN2C(C3=CC(N)=NC(F)=C3)=CN=C2C=C1OCC)(C(C)(C)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 31.25 mg/mL (79.63 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5481 mL 12.7405 mL 25.4810 mL
5 mM 0.5096 mL 2.5481 mL 5.0962 mL
10 mM 0.2548 mL 1.2740 mL 2.5481 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 3.13 mg/mL (7.98 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

RIPK-IN-4RIP kinaseReceptor-interacting protein kinasesRIPKInhibitorinhibitorinhibit

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Product Name:
RIPK-IN-4
Cat. No.:
HY-107978
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