RNA polymerase-IN-4
RNA polymerase-IN-4 is a RNA polymerase inhibitor with an EC50 of 22.81 nM. RNA polymerase-IN-4 exhibits potent anti-influenza virus activity (EC50 = 3.76 nM), relatively low cytotoxicity (CC50 = 29.91 μM). RNA polymerase-IN-4 can be used for the research of infection, such as influenza virus infection.
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- No. CAS: 3040910-48-0
- Fòrmula: C28H25F2N3O4S
- Peso molecular:537.58
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Actividad biológica
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RNA Polymerase |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:BALB/c mice infected with influenza A/WSN/33 (H1N1)[1]
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Dosage:5 and 10 mg/kg
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Administration:Intravenously injection, twice a day from day 2 post-infection
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Result:Alleviated weight loss and reduced lung tissue viral load.
Showed no obvious abnormal toxicity.
Chemical Information
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No. CAS 3040910-48-0
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Peso molecular 537.58
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Fòrmula C28H25F2N3O4S
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SMILES
FC1=C(F)C=CC2=C1CSC3=C(C=CC=C3)[C@H]2N4[C@@H](CC5(CCOCC5)C6)N6C(C(N4C=C7)=C(O)C7=O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RNA polymerase-IN-4 Related Classifications
HY-179029 Related Classifications
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