S-Hexylglutathione
Based on 1 Customer Validation
S-Hexylglutathione is an S-substituted glutathione in which the hydrogen of the thiol has been replaced by a hexyl group. S-Hexylglutathione is also an competitive inhibitor against glutathione-S-transferase. S-Hexylglutathione can be used as an affinity chromatographic ligand for glutathione-S-transferase and glutathione peroxidase.
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- Pureté : 99.82%
- CAS No.: 24425-56-7
- Formule: C16H29N3O6S
- Masse moléculaire:391.48
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
In Vitro
S-Hexylglutathione is bound by human glutathione transferase P1-1 with Kd values of 3.7 μM (Y49F mutant) and 1.27 μM (wild-type), respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 24425-56-7
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Appearance Solid
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Masse moléculaire 391.48
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Formule C16H29N3O6S
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Color White to yellow
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SMILES
OC(CNC([C@H](CSCCCCCC)NC(CC[C@H](N)C(O)=O)=O)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 12.5 mg/mL (31.93 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (270 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Ortiz-Salmerón E, et al. Thermodynamic description of the effect of the mutation Y49F on human glutathione transferase P1-1 in binding with glutathione and the inhibitor S-hexylglutathione. J Biol Chem. 2003 Nov 21;278(47):46938-48. [Content Brief]
[2]. Swope MD, et al. Macrophage migration inhibitory factor interactions with glutathione and S-hexylglutathione. J Biol Chem. 1998 Jun 12;273(24):14877-84. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5544 mL | 12.7720 mL | 25.5441 mL | 63.8602 mL |
| 5 mM | 0.5109 mL | 2.5544 mL | 5.1088 mL | 12.7720 mL | |
| 10 mM | 0.2554 mL | 1.2772 mL | 2.5544 mL | 6.3860 mL | |
| 15 mM | 0.1703 mL | 0.8515 mL | 1.7029 mL | 4.2573 mL | |
| 20 mM | 0.1277 mL | 0.6386 mL | 1.2772 mL | 3.1930 mL | |
| 25 mM | 0.1022 mL | 0.5109 mL | 1.0218 mL | 2.5544 mL | |
| 30 mM | 0.0851 mL | 0.4257 mL | 0.8515 mL | 2.1287 mL |
S-Hexylglutathione Related Classifications
HY-W013754 Related Classifications
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