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Cat. No.: HY-N1328

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Safrolglycol

Safrolglycol is a phenylpropane compound that can be found in the wood of Cinnamomum parthenoxylon. Safrolglycol inhibits the proliferation of human leukemia cells and can be used in leukemia-related research.

For research use only. We do not sell to patients.

CAS No.: 7154-01-0
Formula: C₁₀H₁₂O₄
Molecular Weight:196.20

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Safrolglycol Chemical Structure

CAS No.: 7154-01-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HL-60	IC₅₀	60 μM Compound: 4	Cytotoxicity against human HL60 cells after 48 hrs by CCK8 assay Cytotoxicity against human HL60 cells after 48 hrs by CCK8 assay	[PMID: 26774581]
U-937	IC₅₀	50.8 μM Compound: 4	Cytotoxicity against human U937 cells after 48 hrs by CCK8 assay Cytotoxicity against human U937 cells after 48 hrs by CCK8 assay	[PMID: 26774581]

In Vitro

Safrolglycol (Compound 4) inhibits the proliferation of human leukemia HL-60 cells with an IC₅₀ of 60.0 μM, and suppresses the proliferation of human leukemia U937 cells with an IC₅₀ of 50.8 μM following 48 h of treatment^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 7154-01-0
Molecular Weight 196.20
Formula C₁₀H₁₂O₄
SMILES

OCC(O)CC1=CC=C2OCOC2=C1
Structure Classification
- Others
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Adfa M, et al. Antileukemic activity of lignans and phenylpropanoids of Cinnamomum parthenoxylon. Bioorg Med Chem Lett. 2016;26(3):761-764. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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