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SAR629 

Cat. No.: HY-118653
Handling Instructions

SAR629 is a potent monoglyceride lipase (MGL) covalent inhibitor. SAR629 also inhibits 2-Arachidonoylglycerol (2-AG) degradation.

For research use only. We do not sell to patients.

SAR629 Chemical Structure

SAR629 Chemical Structure

CAS No. : 1221418-42-3

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Description

SAR629 is a potent monoglyceride lipase (MGL) covalent inhibitor. SAR629 also inhibits 2-Arachidonoylglycerol (2-AG) degradation[1][2].

In Vitro

SAR629 is a potent dual inhibitory action on MAGL and fatty acid amide hydrolase (FAAH). SAR629 inhibits rodent monoglyceride lipase (MGL) activity at subnanomolar potencies (IC50 values of 1.1 nM and 219 pM in rat and mouse brain membranes, respectively)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

383.39

Formula

C₂₀H₁₉F₂N₅O

CAS No.
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
SAR629
Cat. No.:
HY-118653
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