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  4. Tetracyclic Triterpenoids
  5. Sarmentogenin

Sarmentogenin is a cardenolide aglycone can be found in rhodexin A and Chrysolina herbacea.

For research use only. We do not sell to patients.

Sarmentogenin

Sarmentogenin Chemical Structure

CAS No. : 76-28-8

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Sarmentogenin Related Antibodies

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Description

Sarmentogenin is a cardenolide aglycone can be found in rhodexin A and Chrysolina herbacea[1][2].

Cellular Effect
Cell Line Type Value Description References
CHO Inhibition
105.751 %
Compound: SARMENTOGENIN
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
[PMID: 23571415]
CHO Inhibition
70.5845 %
Compound: SARMENTOGENIN
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
[PMID: 23571415]
HCT-116 Survival
26 %
Compound: sarmentogenin
Cytotoxicity against human HCT116 cells assessed as survival index at 10 uM after 72 hrs by FMCA method
Cytotoxicity against human HCT116 cells assessed as survival index at 10 uM after 72 hrs by FMCA method
[PMID: 19894733]
HT-29 Survival
63 %
Compound: sarmentogenin
Cytotoxicity against human HT-29 cells assessed as survival index at 10 uM after 72 hrs by FMCA method
Cytotoxicity against human HT-29 cells assessed as survival index at 10 uM after 72 hrs by FMCA method
[PMID: 19894733]
Molecular Weight

390.51

Formula

C23H34O5
CAS No.
SMILES

C[C@@]12[C@@]([C@@]3([H])[C@]([C@@]4([C@](C[C@H](CC4)O)([H])CC3)C)([H])[C@@H](C1)O)(CC[C@@H]2C(CO5)=CC5=O)O
Structure Classification
Initial Source

Chrysolina herbacea
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Sarmentogenin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sarmentogenin76-28-8OthersTLCChrysolina herbacea17-deoxycortisoneMSrhodexin Anatural cardenolideNMRMukaiyama hydrationcardenolide aglyconeInhibitorinhibitorinhibit

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Sarmentogenin
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