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United States

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製品番号: HY-N14147

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Sarmentogenin

Sarmentogenin is a cardenolide aglycone can be found in rhodexin A and Chrysolina herbacea.

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CAS 番号: 76-28-8
分子式: C₂₃H₃₄O₅
分子量:390.51

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Sarmentogenin 構造式

CAS 番号: 76-28-8

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Sarmentogenin is a cardenolide aglycone can be found in rhodexin A and Chrysolina herbacea^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	Inhibition	105.751 % Compound: SARMENTOGENIN	Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM	[PMID: 23571415]
CHO	Inhibition	70.5845 % Compound: SARMENTOGENIN	Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM	[PMID: 23571415]
HCT-116	Survival	26 % Compound: sarmentogenin	Cytotoxicity against human HCT116 cells assessed as survival index at 10 uM after 72 hrs by FMCA method Cytotoxicity against human HCT116 cells assessed as survival index at 10 uM after 72 hrs by FMCA method	[PMID: 19894733]
HT-29	Survival	63 % Compound: sarmentogenin	Cytotoxicity against human HT-29 cells assessed as survival index at 10 uM after 72 hrs by FMCA method Cytotoxicity against human HT-29 cells assessed as survival index at 10 uM after 72 hrs by FMCA method	[PMID: 19894733]

化学情報

CAS 番号 76-28-8
分子量 390.51
分子式 C₂₃H₃₄O₅
SMILES

C[C@@]12[C@@]([C@@]3([H])[C@]([C@@]4([C@](C[C@H](CC4)O)([H])CC3)C)([H])[C@@H](C1)O)(CC[C@@H]2C(CO5)=CC5=O)O
Structure Classification
- Terpenoids
- Tetracyclic Triterpenoids
Initial Source
- Animal
Chrysolina herbacea
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (270 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Song F, et al. Chemoenzymatic synthesis of the cardenolide rhodexin A and its aglycone sarmentogenin. Beilstein J Org Chem. 2025;21:2637-2644. Published 2025 Dec 3. [Content Brief]

[2]. Pasteels JM, et al. Cardiac glycosides in the defensive secretion of Chrysolina herbacea (Coleoptera, Chrysomelidae). Identification, biological role and pharmacological activity. Comp Biochem Physiol C Comp Pharmacol. 1979;63C(1):117-21. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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