SARS-CoV-2-IN-19
SARS-CoV-2-IN-19 (Compound 6g) is a potent inhibitor of SARS-CoV-2 with an EC50 of 8.8 μM. SARS-CoV-2-IN-19 shows potent activity against SARS-CoV-2 helicase (nsp13), a highly conserved enzyme, highlighting a potentiality against emerging HCoVs outbreaks. SARS-CoV-2-IN-19 has the potential for the research of infection diseases.
For research use only. We do not sell to patients.
- CAS No.: 2244991-17-9
- Formula: C33H38N2O6
- Molecular Weight:558.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Helicase |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEL 299 | CC50 |
26.7 μM
Compound: 6g
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Cytotoxicity against HEL 299 cells assessed as reduction in cell viability measured after 1 to 2 hrs by MTS colorimetric assay
Cytotoxicity against HEL 299 cells assessed as reduction in cell viability measured after 1 to 2 hrs by MTS colorimetric assay
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[PMID: 35571875] |
| Vero C1008 | CC50 |
>100 μM
Compound: 6g
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Cytotoxicity against African green monkey Vero E6 cells assessed as reduction in cell viability measured after 1 to 2 hrs by MTS colorimetric assay
Cytotoxicity against African green monkey Vero E6 cells assessed as reduction in cell viability measured after 1 to 2 hrs by MTS colorimetric assay
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[PMID: 35571875] |
Chemical Information
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CAS No. 2244991-17-9
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Molecular Weight 558.66
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Formula C33H38N2O6
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SMILES
CCCOC1=CC=C(C=C1)C2=NC3=C(C(OCCN4CCC5=C(C4)C=C(C(OC)=C5)OC)=C2)C(OC)=CC(OC)=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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