SC-51316
SC-51316 is an oral active angiotensin II receptor antagonist with the IC50 values of 3.6 and 5.1 nM in rat adrenal cortical and rat uterine membrane, respectively. SC-51316 shows antihypertensive activity in vivo and in vitro.
For research use only. We do not sell to patients.
- CAS No.: 133690-62-7
- Formula: C24H29N7O
- Molecular Weight:431.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
All Angiotensin Receptor Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 133690-62-7
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Molecular Weight 431.53
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Formula C24H29N7O
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SMILES
O=C1N(CCCC)N=C(CCCC)N1CC2=CC=C(C3=C(C4=NN=NN4)C=CC=C3)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
[1]. Olins GM, et al. In vitro pharmacology of a nonpeptidic angiotensin II receptor antagonist, SC-51316. J Pharmacol Exp Ther. 1992;261(3):1037-1043. [Content Brief]
[2]. Olins GM, et al. In vivo pharmacology of SC-51316, a nonpeptidic angiotensin II receptor antagonist. Am J Hypertens. 1993;6(7 Pt 1):619-625. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SC-51316 Related Classifications
HY-120776 Related Classifications
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