SCD1 inhibitor-5
SCD1 inhibitor-5 (compound 51) is a SCD1 inhibitor,with the IC50 values of 0.13 μM and 31 μM for H2122 and H1819, respectively. SCD1 inhibitor-5 can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 1673558-59-2
- Formula: C25H18N2O4S
- Molecular Weight:442.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NCI-H2122 | IC50 |
0.13 μM
Compound: 51
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Inhibition of SCD in human NCI-H2122 cells expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent based assay
Inhibition of SCD in human NCI-H2122 cells expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent based assay
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[PMID: 32787093] |
Chemical Information
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CAS No. 1673558-59-2
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Molecular Weight 442.49
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Formula C25H18N2O4S
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SMILES
O=C(C1=CC=C(C(C2=CC=C(C=C2)OCC#C)=O)C=C1)NC3=NC4=C(S3)C=C(OC)C=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SCD1 inhibitor-5 Related Classifications
HY-155209 Related Classifications
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