Anticancer agent 87
Anticancer agent 87 is a spirooxindole-furan derivative with anticancer activity. Anticancer agent 87 can be used for the research of breast adenocarcinoma and human liver cancer.
For research use only. We do not sell to patients.
- Formula: C30H21BrCl2N2O3S
- Molecular Weight:640.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
Anticancer agent 87 (Compound 6f) potently inhibits the viability of MCF7 breast adenocarcinoma cells with an IC50 of 10.3 μM/mL[1].
Anticancer agent 87 potently inhibits the viability of HepG2 liver carcinoma cells with an IC50 of 3.5 μM/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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Molecular Weight 640.37
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Formula C30H21BrCl2N2O3S
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SMILES
O=C1NC2=C(C=CC(Cl)=C2)[C@@]13N4CSCC4[C@@H](C5=CC=C(C6=CC=CC=C6Cl)O5)[C@@H]3C(C7=CC=C(Br)C=C7)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Liver Cancer Modeling
Liver cancer can be classified into primary liver cancer and secondary liver cancer. Secondary liver cancer is the metastatic liver cancer. Primary liver cancer includes hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) and fibrolamellar HCC, of which HCC is the most common form, accounting for approximately 90% of primary liver cancers[1]. HCC mouse models include chemical agent-induced models, transplanted tumor models, and genetic engineered models.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)