DCOIT (Standard)
DCOIT (Standard) (Kathon 930 (Standard)) is the analytical standard of DCOIT (HY-W041308). This product is intended for research and analytical applications. DCOIT (Kathon 930) is an isothiazolinone biocide and environmental pollutant that directly binds to G protein α subunits, with KD values of 0.92 mM and 0.4 mM for Gαs and Gαi, respectively. Binding of DCOIT to Gαi enhances the interaction between Gαi and mitochondrial calcium uniporter (MCU), alters the subcellular distribution of intracellular Ca2+, and activates PKC/MEK/ERK signaling. DCOIT upregulates CYP19a transcription and aromatase activity, thereby disrupting steroid hormone homeostasis. DCOIT is used in studies of reproductive endocrine disruption and environmental toxicology.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 64359-81-5
- Formula: C11H17Cl2NOS
- Molecular Weight:282.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
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HY-W041308
DCOIT -
HY-I0144
Thiazolidine -
HY-P0009A
Cetrorelix acetate -
HY-14789
(R)-Elagolix -
HY-P0051
Lecirelin -
HY-130249
BAY-298 -
HY-P0056A
Histrelin acetate -
HY-P0243
Luteinizing Hormone Releasing Hormone (LH-RH), salmon -
HY-P0053
Fertirelin -
HY-P1808
LGnRH-III, lamprey -
HY-125611
Fluorogestone acetate -
HY-14789R
(R)-Elagolix (Standard)
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 64359-81-5
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Molecular Weight 282.23
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Formula C11H17Cl2NOS
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SMILES
O=C1N(CCCCCCCC)SC(Cl)=C1Cl
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Synonyms
Kathon 930 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DCOIT (Standard) Related Classifications
HY-W041308R Related Classifications
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Keywords
- DCOIT (Standard)
- 64359-81-5
- Kathon 930 (Standard)
- Reference Standards
- Environmental Pollutants
- GnRH Receptor
- H295R cells
- hypothalamus-pituitary-gonadal axis
- Gαi
- isothiazolinone biocide
- blood-brain barrier permeability
- mitochondrial calcium uniporter
- reproductive endocrine disruption
- marine medaka
- MAPK pathway
- O. melastigma
- Inhibitor
- inhibitor
- inhibit