237 Results for "

Synthetic intermediates

" in MedChemExpress (MCE) Product Catalog:
Products (237)

237 Results for "Synthetic intermediates" in MCE Product Catalog:

Cat. No.: HY-W106109
CAS No.: 607-66-9
Target:  

Drug Intermediate

Research Areas:  

Others

2-Hydroxy-4-methylquinoline is a synthetic intermediate. 2-Hydroxy-4-methylquinoline is formed via cyclization of acetoacetanilide under the action of concentrated sulfuric acid through the Conrad-Limpach-Knorr synthesis. 2-Hydroxy-4-methylquinoline can be used in studies related to the synthesis of chemotherapeutic agents .
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Cat. No.: HY-134349A
Synonyms: 8-Piperidino-NAD+ sodium
Target:  

Endogenous Metabolite

Research Areas:  

Others

8-PIP-NAD+ (sodium) (8-Piperidino-NAD+ (sodium)) is a derivative of the signaling molecule and enzyme cofactor NAD+ (HY-B0445). 8-PIP-NAD+ (sodium) can be used in the determination of poly(ADP-ribose) polymerase (PARP) target proteins. 8-PIP-NAD+ (sodium) is a synthetic intermediate in the synthesis of cyclic ADP-ribose (cADPR) derivatives .
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Cat. No.: HY-184695
CAS No.: 2755836-98-5
Research Areas:  

Cancer

NH2-C16-azide is a 16-azidohexadecylamine derivative and synthetic intermediate, which can serve as a PROTAC Linker. NH2-C16-azide is applicable to research related to PROTAC synthesis, such as acting as the linker for PROTAC CDK9 degrader-13 (HY-184693) .
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Cat. No.: HY-W003129
CAS No.: 22918-01-0
2-Bromo-4-chloropyridine is a halogenated pyridine derivative that serves as a synthetic intermediate. 2-Bromo-4-chloropyridine undergoes Suzuki-Miyaura coupling with 4-tert-butylphenylboronic acid (HY-W007389). 2-Bromo-4-chloropyridine facilitates the construction of compounds with broad-spectrum antibacterial activity .
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Cat. No.: HY-W004498
CAS No.: 389-58-2
Synonyms: 4H-Cyclopenta[1,2-b:5,4-b']dithiophene
Target:  

Drug Intermediate MOFs

Research Areas:  

Others

4H-Cyclopenta[2,1-b:3,4-b']dithiophene (4H-Cyclopenta[1,2-b:5,4-b']dithiophene) is a methylene-bridged fused-ring thiophene-based building block, which serves as a synthetic intermediate for organic photonic and electronic materials .
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Cat. No.: HY-128753
CAS No.: 1114-34-7
Purity:  ≥98.0%
D-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose with significant potential for pharmaceutical synthesis. D-Lyxose serves as a starting material for antitumor agents (such as α-galactosylceramide-based immunostimulants). D-Lyxose acts as a precursor for L-nucleoside analogs used in the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars (such as L-ribose) .
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Cat. No.: HY-200864
CAS No.: 2654826-81-8
E3 ligase Ligand 64-2-(4-hydroxypiperidin-4-yl) acetic acid is an E3 ligase-linker conjugate. E3 ligase Ligand 64-2-(4-hydroxypiperidin-4-yl) acetic acid serves as a synthetic intermediate for the IRAK4-targeting PROTAC APH003 (HY-184915) .
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Cat. No.: HY-W004121
CAS No.: 1623-93-4
4-Biphenylsulfonyl chloride is a synthetic intermediate that participates in the sulfonamide formation reaction to synthesize antiproliferative compounds. The derivatives of 4-Biphenylsulfonyl chloride inhibit human head and neck squamous cell carcinoma (HNSCC) cells by increasing PTEN expression and inhibiting the PI3K/Akt/mTOR pathway. 4-Biphenylsulfonyl chloride can be used in the development of anticancer drugs for HNSCC .
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Cat. No.: HY-W007273R
CAS No.: 18202-10-3
11-Dodecyn-1-ol (Standard) is the analytical standard of 11-Dodecyn-1-ol (HY-W007273). This product is intended for research and analytical applications. 11-Dodecyn-1-ol is a synthetic intermediate of the sex pheromone (Z,E)-11,13,15-Hexadecatrienyl acetate for Thaumetopoea processionea .
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Cat. No.: HY-W017378R
CAS No.: 700-13-0
Research Areas:  

Others

Trimethylhydroquinone (Standard) is the analytical standard of Trimethylhydroquinone (HY-W017378). This product is intended for research and analytical applications. Trimethylhydroquinone is an active compound intermediate. Trimethylhydroquinone can condense with isophytol or phytol to produce synthetic Vitamin E (HY-B1278A). Trimethylhydroquinone serves as the parent compound for the synthesis of trimethylhydroquinone derivatives with antioxidant, anti-allergic, and 5-lipoxygenase inhibitory activities .
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Cat. No.: HY-161703
CAS No.: 157309-10-9
Target:  

Adenosine Deaminase

Research Areas:  

Cardiovascular Disease

2-Hydroxy-3′-O-methyladenosine is a synthetic intermediate product that can be used in the research of ischemic heart disease, cerebrovascular disease, kidney disease, inflammatory allergies and other diseases. 2-phenylamino-N6,2'-O-dimethyladenosine produced from 2-Hydroxy-3′-O-methyladenosine is an inhibitor of adenosine deaminase with a Ki of 13 nM .
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Cat. No.: HY-176068
Target:  

Androgen Receptor

Research Areas:  

Cancer

3-Cl-Pyridine-amide-acrylaldehyde-piperazine is a synthetic intermediate of LO-4-25 (HY-176067). LO-4-25 is an androgen receptor (AR) DNA binding domain ligand linked via a linker to the truncated fumaramide handle. LO-4-25 shows robust degradation of both AR and AR-V7 in 22Rv1 cells .
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Cat. No.: HY-189490
CAS No.: 1227698-30-7
Research Areas:  

Others

Hercynylcysteine sulfoxide is a synthetic precursor of Ergothioneine (HY-N1914), and it spontaneously converts to Ergothioneine in the presence of pyridoxal phosphate (PLP). Hercynylcysteine sulfoxide is produced via the fusion enzyme complex NcEgt1‑1/CtEgtB-catalyzed conversion of L-histidine and L-cysteine, and serves as an intermediate in the ergothioneine biosynthetic pathway of Schizosaccharomyces pombe and engineered Escherichia coli BL21 (DE3) .
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Cat. No.: HY-32149S
CAS No.: 2363787-31-7
1-Bromo-3-iodobenzene-d4 is the deuterium labeled 1-Bromo-3-iodobenzene (HY-32149). 1-Bromo-3-iodobenzene is a biochemical reagent and an important organic synthetic intermediate. 1-Bromo-3-iodobenzene can be used for the synthesis of other active compounds .
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Cat. No.: HY-W016689
CAS No.: 2010-06-2
Target:  

Drug Intermediate

Research Areas:  

Cancer

2-Amino-4-phenylthiazole is a synthetic intermediate useful for pharmaceutical synthesis. 2-Amino-4-phenylthiazole can be used to synthesize suberoylanilide hydroxamic acid (SAHA) analogs with cancer cell growth inhibitory activities. 2-Amino-4-phenylthiazole also can be used to synthesize ketone histone deacetylase inhibitors with antitumor activity in vivo .
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Cat. No.: HY-W017601
CAS No.: 873-32-5
Synonyms: o-Chlorobenzonitrile
Target:  

Parasite

Research Areas:  

Infection Inflammation/Immunology

2-Chlorobenzonitrile (o-Chlorobenzonitrile) is an antimalarial agent. 2-Chlorobenzonitrile exerts its effects through non-specific interactions with biological membranes. 2-Chlorobenzonitrile exhibits growth inhibitory activity against Tetrahymena pyriformis. 2-Chlorobenzonitrile serves as a synthetic intermediate for azo dyes and the antimalarial agent Quetiapine nitrate. 2-Chlorobenzonitrile possesses potential anti-inflammatory activity .
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Cat. No.: HY-W039943
CAS No.: 121584-52-9
Target:  

Drug Intermediate

Research Areas:  

Inflammation/Immunology Cancer

Acetyl-cyclosporin A aldehyde is an acetylated derivative of Cyclosporin A (HY-B0579) with a reducible aldehyde group. Acetyl-cyclosporin A aldehyde serves as a synthetic intermediate for the calcineurin inhibitor Voclosporin (HY-106638). Acetyl-cyclosporin A aldehyde can act as a substrate for ruthenium nanocatalyzed reductive deuteration reactions, producing the corresponding deuterated alcohol with selective deuterium incorporation at the α-position of the oxygen atom .
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Cat. No.: HY-76547R
CAS No.: 99-94-5
Synonyms: 4-Methylbenzoic acid (Standard)
p-Toluic acid (Standard) is the analytical standard of p-Toluic acid. This product is intended for research and analytical applications. p-Toluic acid (4-Methylbenzoic acid), coumarin, is a substituted benzoic acid. p-Toluic acidis synthetic p-aminomethylbenzoic acid (PAMBA), intermediates such as p-toluonitrile. p-Toluic acidMay have potential reproductive toxicity, press 1g/kgRepeated administration of doses can produce a variety of adverse effects on the epididymis .
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Cat. No.: HY-W001240
CAS No.: 1993-03-9
2-Fluorophenylboronic acid is an organic synthesis intermediate belonging to the fluorinated arylboronic acid class. The electron-withdrawing fluorine substituent in 2-Fluorophenylboronic acid reduces its pKa, thereby enhancing boronate bond formation with diols. 2-Fluorophenylboronic acid serves as a key synthetic intermediate for inhibitors of Plasmodium phosphatidylinositol 4-kinase IIIβ (PI4K). 2-Fluorophenylboronic acid can also be used to functionalize linear polyglycerols for constructing dual dynamic covalent cross-linked hydrogels that support 3D tumor spheroid culture of various cancer cells. 2-Fluorophenylboronic acid is applicable to research related to malaria and tumors .
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Cat. No.: HY-125946
CAS No.: 145667-75-0
Purity:  99.86%
Target:  

Drug Intermediate

Research Areas:  

Endocrinology

Latanoprost lactone diol is a small organic molecule derived from Prostaglandin F2α (HY-12956), serving as a key synthetic intermediate and inactive metabolism-related form of Latanoprost (HY-B0577). Latanoprost lactone diol is significantly upregulated in hypothyroid rats, and its level can be reversed by crude polysaccharide, lactone and oligosaccharide fractions from the rhizome of Atractylodis macrocephalae. Latanoprost lactone diol can be used in studies related to hypothyroidism .
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