2946 Results for "

TYR

" in MedChemExpress (MCE) Product Catalog:
Products (2946)

2946 Results for "TYR" in MCE Product Catalog:

Cat. No.: HY-P5921
CAS No.: 152618-71-8
Synonyms: TsTx-Kα
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Tityustoxin-Kα (TsTx-Kα) is an inhibitor of potassium voltage-gated channels. Tityustoxin-Kα shows a dose-dependent block of the sustained outward current in cultured hippocampal neurons .
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Cat. No.: HY-106224AS1
Synonyms: Hypocretin-1-13C18,15N3 (human, rat, mouse) TFA
Orexin A- 13C18, 15N3 (human, rat, mouse) ((Hypocretin-1- 13C18, 15N3 (human, rat, mouse)) TFA is the 13C- and 15N-labeled Orexin A (human, rat, mouse) (HY-106224). Orexin A (human, rat, mouse) (Hypocretin-1 (human, rat, mouse)), a 33 amino acid excitatory neuropeptide, orchestrates diverse central and peripheral processes. Orexin A (human, rat, mouse) binds and activates two types of G protein-coupled receptors, the orexin-1 receptor (OX1R) and the orexin-2 receptor (OX2R). Orexin A (human, rat, mouse) has a role in the regulation of feeding behavior. Orexin A (human, rat, mouse) is an effective anti-nociceptive and anti-hyperalgesic agent in mice and rats .
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Cat. No.: HY-P10230
CAS No.: 207410-26-2
Target:  

Bacterial

Research Areas:  

Infection

Sublancin is an antimicrobial peptide, which inhibits DNA replication, transcription and translation, without affecting membrane integrity. Sublancin suppresses glucose uptake for the competition of phosphotransferase system (PTS). Sublancin inhibits B. subtilis strain 168 ΔSPβ with MIC of 0.312 μM .
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Cat. No.: HY-P10775
Research Areas:  

Cancer

BT1769 is a MT1-MMP-targeted (KD = 3.35 nM) Bicycle toxin conjugate. BT1769 can be used in the study for osteosarcoma. BT1769 consists of a novel bicyclic targeting peptide that selectively binds MT1-MMP; a cytotoxin MMAE; and an enzymatically cleavable dipeptide linker .
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Cat. No.: HY-P10801
Synonyms: C46 peptide
Target:  

HIV

Research Areas:  

Infection

mC46 (C46) peptide is a membrane-associated fusion peptide inhibitor. mC46 peptide potently inhibits HIV-1 replication and entry. mC46 also inhibits CCR5-tropic, CXCR4-tropic, and dual-tropic HIVs, SIV, and SHIV .
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Cat. No.: HY-P10881
CAS No.: 2758595-29-6
Research Areas:  

Metabolic Disease

Ganipatide is a 1-31-Glucose-dependent insulinotropic polypeptide. Ganipatide is promising for research of diabetes .
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Cat. No.: HY-P11237
CAS No.: 2869147-44-2
Synonyms: CT-388
Enicepatide (CT-388) is a cAMP signal-biased dual GLP-1R and GIPR agonist peptide, with an EC50 value of 0.087 nM for GLP-1R cAMP, and an EC50 value of 2.47 nM for GIPR cAMP. Enicepatide activates the cAMP signaling pathway, while recruiting only minimal amounts of β-arrestin-2 at both targets and reducing receptor internalization levels. Enicepatide improves glycemic control, reduces body weight, suppresses appetite, and ameliorates the pathological conditions of metabolic dysfunction-associated steatohepatitis. Enicepatide can be used in the research of obesity, type 2 diabetes, and metabolic dysfunction-associated steatohepatitis .
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Cat. No.: HY-P11245
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

NN1213, a long-acting human amylin peptide analog, is a selective Amylin receptor agonist with EC50 values of 0.177 and 0.262 nM for hAMY3R and rAMY3R, respectively. NN1213 significantly reduces food intake and fat mass. NN1213 can reduce body weightin diet-induced obese rats. NN1213 can be used for the research of obesity .
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Cat. No.: HY-P11245A
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

NN1213 acetate, a long-acting human amylin peptide analog, is a selective Amylin receptor agonist with EC50 values of 0.177 and 0.262 nM for hAMY3R and rAMY3R, respectively. NN1213 acetate significantly reduces food intake and fat mass. NN1213 acetate can reduce body weightin diet-induced obese rats. NN1213 acetate can be used for the research of obesity .
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Cat. No.: HY-P1426A
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

AmmTX3 TFA is a peptide toxin identified from the venom of the scorpion Androctonus mauretanicus. AmmTX3 TFA is a highly specific blocker of Kv4 channels, which selectively and almost completely blocks transient A-type K + currents with a Ki of 131 nM. AmmTX3 TFA induces epileptiform behaviors and causes death in mice receiving intracerebroventricular injection. AmmTX3 TFA increases the excitability of dentate gyrus granule cells, reduces GABAergic inhibition, enhances and stabilizes the EPSP-spike component of long-term potentiation, and impairs reference memory. AmmTX3 TFA can be used in research related to pain, epilepsy, and autism spectrum disorder .
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Cat. No.: HY-P3196
CAS No.: 1673565-40-6
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Tozuleristide is a tumor-targeting agent covalently conjugated to a derivative of the near-infrared fluorescent dye indocyanine green (ICG). Tozuleristide has the ability to penetrate the blood-brain barrier. Tozuleristide can be used in research related to fluorescence-guided surgery (FGS) .
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Cat. No.: HY-P4157A
Target:  

MDM-2/p53 Apoptosis

Research Areas:  

Metabolic Disease

FOXO4-DRI acetate is a cell-permeable peptide antagonist that blocks the interaction of FOXO4 and p53. FOXO4-DRI acetate is a senolytic peptide that induces apoptosis of senescent cells .
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Cat. No.: HY-P4884
CAS No.: 285554-31-6
Target:  

Amyloid-β

Research Areas:  

Others

Amyloid β-Protein (1-46) is aAβ Fragment.
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Cat. No.: HY-P6008
Synonyms: MLN peptide
Target:  

Calcium Channel

Research Areas:  

Cardiovascular Disease

Myoregulin (MLN peptide) is a member of the regulin family. Myoregulin regulates muscle performance by modulating intracellular calcium handling. Myoregulin interactes directly with sarcoplasmic reticulum Ca 2+-ATPase (SERCA) and impedinf Ca 2+ uptake into the sarcoplasmic reticulum .
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Cat. No.: HY-P6008A
Synonyms: MLN peptide TFA
Target:  

Calcium Channel

Research Areas:  

Cardiovascular Disease

Myoregulin (MLN peptide) TFA is a member of the regulin family. Myoregulin TFA regulates muscle performance by modulating intracellular calcium handling. Myoregulin TFA interactes directly with sarcoplasmic reticulum Ca 2+-ATPase (SERCA) and impedinf Ca 2+ uptake into the sarcoplasmic reticulum .
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Cat. No.: HY-P6013
Target:  

Calcium Channel

Research Areas:  

Others

wt hMLN is a microprotein that inhibits of SR Ca 2+ pump (SERCA). wt hMLN plays an important role in skeletal muscle calcium homeostasis .
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Cat. No.: HY-P1838
CAS No.: 166798-69-2
Research Areas:  

Cardiovascular Disease

Proadrenomedullin (45-92), human is a peptide corresponding to amino acids 45-92 of human preproadrenomedullin. Proadrenomedullin (45-92), human has a longer half-life, is relatively stable and is produced in equimolar amounts to adrenomedullin (ADM), making it a surrogate for plasma levels of ADM gene products .
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Cat. No.: HY-P2313
CAS No.: 372146-20-8
Synonyms: HβD-2
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Human β-defensin-2 (HβD-2) is a small cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by a number of epithelial cells.Human β-defensin-2 has antimicrobial activity against gram-negative bacteria and Candida, but not gram-positive Staphylococcus aureus . Human β-defensin-2 can be used for the study of colitis .
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Cat. No.: HY-P4975
CAS No.: 209615-75-8
Target:  

Inhibitory Antibodies

Research Areas:  

Others

CART (61-102) (rat) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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Cat. No.: HY-P5159
Target:  

Sodium Channel

Research Areas:  

Inflammation/Immunology

Crotamine is a Na + channel modulator. Crotamine is a 42 amino acid toxin cross-linked by three disulfide bridges. Crotamine has analgesic activity. Crotamine also interacts with lipid membranes and shows myonecrotic activity. Crotamine can be isolated from Crotalus durissus terrificus venom .
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