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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
370 Results for "
Complement
" in MedChemExpress (MCE) Product Catalog:
Products (370)
370 Results for "Complement" in MCE Product Catalog:
Cat. No.: HY-P10868
CAS No.: 2056232-82-5
Synonyms: RLS-0071
Target:
Research Areas:
Cat. No.: HY-P1345C
Research Areas:
Cat. No.: HY-P991425
Target:
Research Areas:
Cat. No.: HY-P992482
Research Areas:
Cat. No.: HY-P99757
CAS No.: 2278244-14-5
Synonyms: Hu3F8-BsAb
Cat. No.: HY-W015815
CAS No.: 6960-22-1
Cat. No.: HY-P10868A
Synonyms: RLS-0071 TFA
Target:
Research Areas:
Cat. No.: HY-P991547
CAS No.: 922534-56-3
Research Areas:
Cat. No.: HY-L207
661 compounds
Metabolomics is the large-scale study of cellular metabolic complement, with proven utility in both basic and applied studies of plants, microorganisms, and mammals. As an important tool for the study of complex biological systems, metabolomics monitors the complex molecular networks that exist in the natural flow of information from genes to mRNA and proteins to organisms. The metabolome is composed of biomolecules that most closely resemble the phenotype of an organism, and changes in its composition can easily lead to the production of diseases. Therefore, metabolomics has received much attention in drug target discovery, drug response and translational research of disease mechanisms. Mass spectrometry-based metabolomics methods can simultaneously detect and quantify thousands of metabolite signatures, thereby characterizing the pathophysiological mechanisms of various biomedical symptoms.
MCE can provide 661 mass spectrometry human endogenous metabolites that can be used for metabolite identification and quantification, functional cell detection and phenotypic screening of mass spectrometry.
Cat. No.: HY-L026P
3,298 compounds
New drug development is a time-consuming and high-cost process. Drug repurposing (also called drug repositioning, reprofiling or re‑tasking) offers various advantages over developing an entirely new drug for a given indication, such as lower risk and less investment. Clinical drugs have confirmed bioactivities, clear mechanisms and high safety that are suitable for drug repurposing.
MCE owns a unique collection of 3,298 clinical compounds that refer to various research areas including anti-cancer, anti-infection, anti-inflammation, nervous disease. Those compounds are of detailed information on clinical development status, research area, targets, etc. Clinical Compound Library Plus, with powerful screening capability, further complements Clinical Compound Library (HY-L026) by adding some compounds with low solubility or solution stability (Part B) to this library. All those supplementary are supplied in powder form.
Cat. No.: HY-P71006
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VSIG4; V-Set And Immunoglobulin Domain Containing 4; Z39IG; CRIg; Complement Receptor Of The Immunoglobulin Superfamily; V-Set And Immunoglobulin Domain-Containing Protein 4; Protein Z39Ig; Ig Superfamily Protein
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P71423
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VSIG4; V-Set And Immunoglobulin Domain Containing 4; Z39IG; CRIg; Complement Receptor Of The Immunoglobulin Superfamily; V-Set And Immunoglobulin Domain-Containing Protein 4; Protein Z39Ig; Ig Superfamily Protein
Species:
Human
Source:
HEK293
Cat. No.: HY-P71424
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VSIG4; V-Set And Immunoglobulin Domain Containing 4; Z39IG; CRIg; Complement Receptor Of The Immunoglobulin Superfamily; V-Set And Immunoglobulin Domain-Containing Protein 4; Protein Z39Ig; Ig Superfamily Protein
Species:
Human
Source:
HEK293
Cat. No.: HY-P76699
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VSIG4; V-Set And Immunoglobulin Domain Containing 4; Z39IG; CRIg; Complement Receptor Of The Immunoglobulin Superfamily; V-Set And Immunoglobulin Domain-Containing Protein 4; Protein Z39Ig; Ig Superfamily Protein
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P705243
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: VSIG4; V-Set And Immunoglobulin Domain Containing 4; Z39IG; CRIg; Complement Receptor Of The Immunoglobulin Superfamily; V-Set And Immunoglobulin Domain-Containing Protein 4; Protein Z39Ig; Ig Superfamily Protein
Species:
Human
Source:
HEK293
Cat. No.: HY-P990954
CAS No.: 2850355-94-9
Synonyms: IMM-0306
Amulirafusp alfa (IMM-0306) is a fusion protein of CD20 monoclonal antibody (mAb) with the CD47 binding domain of SIRPα, with human CD20 Kd 2.45 nM and human CD47 Kd 4.91 nM. Amulirafusp alfa binds to CD20 and CD47 on B cells, engages FcɣR, blocks CD47-SIRPα interaction, activates macrophages, NK cells, and complement cascade, mediates phagocytosis and cytotoxicity, inhibits apoptosis of Jurkat-CSR cells, reverses IL-16 tumor-promoting effects, and binds human/cynomolgus CD47 but not mouse/rat CD47. Amulirafusp alfa can be used for the research of hematological malignancies, relapsed or refractory CD20-positive B-cell non-Hodgkin’s lymphoma, relapsed or refractory B-cell non-Hodgkin lymphoma, and activated B-cell-like diffuse large B-cell lymphoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
