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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
138 Results for "
5-HT2-receptor
" in MedChemExpress (MCE) Product Catalog:
Products (138)
138 Results for "5-HT2-receptor" in MCE Product Catalog:
Cat. No.: HY-12714
CAS No.: 37686-84-3
Synonyms: Tergurid; Terguride; trans-Dihydrolisuride
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TDHL (Tergurid) is a dopamine receptor agonist with a Kd of 0.39 nM for D2 receptor and an orally available 5-HT-2 receptor antagonist.
Cat. No.: HY-106584
CAS No.: 89419-40-9
Synonyms: Clospipramine
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Mosapramine (Clospipramine) is an orally active antipsychotic agent and one of the metabolites of Clocapramine (HY-B2073) after oral absorption. Mosapramine exerts its effects by specifically binding to striatal dopamine D2 receptors and frontal lobe 5-HT2 receptors, with a D2/5-HT2 receptor occupancy ratio of 7.4. Mosapramine induces typical neuropharmacological responses in rat brain regions, including extrapyramidal symptoms, hyperprolactinemia, increased salivation, constipation, and upregulated Fos protein expression. Mosapramine also features a reduced incidence of weight loss. Mosapramine is applicable to research related to schizophrenia .
Cat. No.: HY-14940S
CAS No.: 1217617-73-6
Synonyms: MDL100907-d4 hydrochloride; M 100907-d4 hydrochloride
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Amperozide is an atypical antipsychotic that acts as an antagonist of the 5-HT2 receptor with a Ki value of 26 nM. Amperozide has a low affinity for D2 receptors .
Cat. No.: HY-W009754
CAS No.: 87691-87-0
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Antidepressant agent 10 is an orally active antidepressant compound that inhibits the serotonin 5-HT1A and 5-HT2 receptors, with corresponding IC50 values of 190 nM and 110 nM, respectively .
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SB 206553 is a 5-HT2C inverse agonist. SB 206553 can attenuate methamphetamine-seeking in rats. SB 206553 has activity for 5-HT2 receptor ligands in HEK-293 or CHO-K1 cells expressing human recombinant 5-HT2 receptors with pKi values of 5.6 nM (5-HT2A), 7.7 nM (5-HT2B) and 7.8 nM (5-HT2C), respectively. SB 206553 can be used for the research of psychostimulant abuse disorders .
Synonyms: R 64 766-d4
Cat. No.: HY-100993
CAS No.: 97469-12-0
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Altanserin can synthesize Fluorine-18 Altanserin. Fluorine-18 Altanserin binds to the brain 5HT2 receptors .
Cat. No.: HY-106407
CAS No.: 135928-30-2
Synonyms: Org 4428; ADL 6906
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Beloxepin (Org 4428) is an orally active synaptosomal noradrenalin reuptake inhibitor and a 5-HT2 receptor antagonist. Beloxepin shows about 100-fold less affine for other monoamine carriers. Beloxepin has antidepressant and pain-relieving effects .
Cat. No.: HY-14940A
CAS No.: 175673-57-1
Synonyms: (S)-MDL100907; (S)-M 100907
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(S)-Volinanserin is an isform of Volinanserin (HY-14940). Volinanserin is a potent and selective antagonist of 5-HT2 receptor, with a Ki of 0.36 nM, and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 and DA D2 receptors. Volinanserin has antipsychotic activity.
Cat. No.: HY-U00365
CAS No.: 191592-09-3
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5-HT2 antagonist 1 is a potent antagonist of 5-HT2 receptor, with weak α1 adrenoceptor blocking activity.
Cat. No.: HY-17410S
CAS No.: 1071167-49-1
Cat. No.: HY-10563
CAS No.: 125926-17-2
Synonyms: MCI-9042 free acid
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Sarpogrelate (MCI-9042) is a new, specific orally active 5-HT2 receptor antagonist, Sarpogrelate increases platelet aggregation and has hemostasis effect, and can be used for the research of Buerger’s disease .
Cat. No.: HY-13575S1
CAS No.: 1346599-86-7
Synonyms: AD-5423-d5
Cat. No.: HY-B0352A
CAS No.: 61337-87-9
Synonyms: (S)-Org3770; (S)-6-Azamianserin
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(S)-Mirtazapine ((S)-Org3770) is a S(+)-enantiomer of Mirtazapine with pronociceptive properties in an animal model of acute thermal nociception. (S)-Mirtazapine is a stereoselective 5-HT2 receptor antagonist. (S)-Mirtazapine is metabolized by CYP2D6 and CYP1A2 .
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DuP 734 is a sigma receptor antagonist. DuP 734 is a selective and potent sigma and 5-HT2 receptor ligand with weak affinity for D2 receptors. DuP 734 may have antipsychotic activity without the liability of motor side effects typical of neuroleptics .
Cat. No.: HY-11018B
CAS No.: 666179-96-0
Synonyms: R 64 766 mesylate
Research Areas:
Risperidone mesylate(R 64 766 mesylate) is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively.
Cat. No.: HY-17410A
CAS No.: 1299470-39-5
Synonyms: HP 873 hydrochloride
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Iloperidone hydrochloride (HP 873 hydrochloride) is a D2/5-HT2 receptor antagonist. Iloperidone hydrochloride is an atypical antipsychotic for the schizophrenia symptoms .
Cat. No.: HY-W1023070
CAS No.: 144734-44-1
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4-fluoro MBZP is a new psychoactive substance that belongs to the phenylpiperazine class of compounds and can be used to study the 5-HT2 receptors in the central nervous system .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
