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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
41 Results for "
GPR120
" in MedChemExpress (MCE) Product Catalog:
Products (41)
41 Results for "GPR120" in MCE Product Catalog:
Cat. No.: HY-111353R
CAS No.: 1234844-11-1
Research Areas:
GPR120 Agonist 2 (Standard) is the analytical standard of GPR120 Agonist 2 (HY-111353). This product is intended for research and analytical applications. GPR120 Agonist 2 (example 206) is a GPR120 agonist that can be uesd for the study of type II diabetes and diseases associated with poor glycemic control .
Cat. No.: HY-15589R
CAS No.: 885101-89-3
Research Areas:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology
GW9508 (Standard) is the analytical standard of GW9508. This product is intended for research and analytical applications. GW9508 is a potent and selective G protein-coupled receptors FFA1 (GPR40) and GPR120 agonist with pEC50s of 7.32 and 5.46, respectively. GW9508 shows ~100-fold selectivity for GPR40 over GPR120. GW9508 is inactive against other GPCRs, kinases, proteases, integrins and PPARs. GW9508 is a glucose-sensitive insulin secretagogue and an ATP-sensitive potassium (KATP) channels opener. Anti-inflammatory and anti-atherosclerotic activities .
Cat. No.: HY-176838
CAS No.: 1609286-95-4
Target:
Research Areas:
LXT34 (Example 2) is a GPR120 agonist. LXT34 has an anti-inflammatory activity. LXT34 promotes GLP-1 formation in the gastrointestinal tract and improves insulin resistance in macrophages and pancreas cells. LXT34 can be used for inflammatory diseases, such as type 2 diabetes, obesity and non-alcoholic fatty liver research .
Cat. No.: HY-Y1624
CAS No.: 10465-81-3
Synonyms: ADDP; SR 4077
Target:
Research Areas:
1,1'-(Azodicarbonyl)-dipiperidine (ADDP) can be used in the condensation reaction of alcohols with acidic compounds. 1,1'-(Azodicarbonyl)-dipiperidine can also be used in the synthesis of GPR120 agonists with antidiabetic activity, as well as the synthesis of triple agonists for PPARα, PPARγ, and PPARδ. 1,1'-(Azodicarbonyl)-dipiperidine can be used in metabolic disease research .
Cat. No.: HY-W770410
CAS No.: 2748638-71-1
Cat. No.: HY-N0040R
CAS No.: 11021-13-9
Synonyms: Ginsenoside C (Standard)
Cat. No.: HY-W011303R
CAS No.: 554-62-1
Synonyms: 4-Hydroxysphinganine (Standard)
Cat. No.: HY-W727728
CAS No.: 1544739-75-4
Target:
Research Areas:
MK-8666 is a potent and selective partial GPR40 agonist (EC50 = 0.54 nM for human GPR40). MK-8666 shows selectivity over GPR119, GPR43, GPR41, GPR120, and other G-protein-coupled receptors (GPCRs). MK-8666 reduces glucose in the rodent. MK-8666 can be used for type 2 diabetes research [1][2].
Cat. No.: HY-120657S
CAS No.: 2704278-85-1
Cat. No.: HY-100881R
CAS No.: 1374516-07-0
Research Areas:
TUG-891 (Standard) is the analytical standard of TUG-891. This product is intended for research and analytical applications. TUG-891 is a potent and selective agonist for the long chain free fatty acid (LCFA) receptor 4 (FFA4/GPR120) .
Cat. No.: HY-N2540R
CAS No.: 68745-38-0
Synonyms: (±)-5,7-Dihydroxyflavanone (Standard); NSC 43318 (Standard)
Cat. No.: HY-RS04877
Target:
Research Areas:
FFAR4 Human Pre-designed siRNA Set A contains three designed siRNAs for FFAR4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-121212R
CAS No.: 1253909-57-7
Research Areas:
Desmethyl Sibutramine (hydrochloride) (Standard) is the analytical standard of Desmethyl Sibutramine (hydrochloride). This product is intended for research and analytical applications. Icosabutate is an orally active engineered fatty acid and a dual FFAR1/FFAR4 (GPR40/GPR120) agonist with EC50 values of 10 μM and 15.5 μM, respectively. Icosabutate acts as a partial agonist of PPAR-α, with an EC50 of 208 nM. Icosabutate inhibits the arachidonic acid cascade and exhibits antioxidant and anti-apoptotic activities. Icosabutate can be used in the research of nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis, and atherosclerosis .
Cat. No.: HY-W011303S
Synonyms: 4-Hydroxysphinganine-d7
Cat. No.: HY-120657R
CAS No.: 1481636-31-0
Target:
Cat. No.: HY-120657S1
CAS No.: 2748208-06-0
Cat. No.: HY-144026S
CAS No.: 1809222-43-2
Cat. No.: HY-115643
CAS No.: 2896777-27-6
Target:
Research Areas:
AZ13581837 is an orally active GPR120 agonist with an EC50 of 5.2 nM for human GPR120. AZ13581837 signals through Gαq, Gαs, and β-arrestin pathways, reduces cAMP production, stimulates GLP-1 secretion, induces glucose lowering, and increases insulin secretion. AZ13581837 can be used for the research of type 2 diabetes .
Cat. No.: HY-182404
CAS No.: 337495-81-5
Target:
Research Areas:
Anticancer agent 316 (Compound 1) is an anticancer agent. Anticancer agent 316 exerts anticancer activity against colorectal cancers expressing GPR120. Anticancer agent 316 can be used in the research of colorectal cancer .
Cat. No.: HY-RS18817
Target:
Research Areas:
Ffar4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ffar4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
