147 Results for "

HD

" in MedChemExpress (MCE) Product Catalog:
Products (147)

147 Results for "HD" in MCE Product Catalog:

Cat. No.: HY-P5407
CAS No.: 798569-33-2
HD5 is an innate immune effector peptide and SARS-CoV Inhibitor. HD5 binds to the ligand-binding domain of angiotensin-converting enzyme-2 (ACE2) via multiple hydrogen bonds to competitively block the receptor, shielding it from viral recognition. HD5 can be used for the research of COVID-19, HPV16 infection, epithelial ovarian cancer, small-cell lung cancer, and colon cancer .
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Cat. No.: HY-155941
CAS No.: 624-00-0
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

5-Hydroxydecanoic acid (5-HD) is a KATP channel antagonist,which has the effect of blocking the K KATP channel only during ischaemia by competing with the ATP binding site and does not affect pancreatic KATP channels .
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Cat. No.: HY-W008269
CAS No.: 76985-09-6
Research Areas:  

Others

H-D-2-Nal-OH is an alanine derivative .
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Cat. No.: HY-14328
CAS No.: 170858-33-0
Purity:  99.84%
Synonyms: PNU-101387G; U-101387G
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Sonepiprazole (PNU-101387G) is a selective D4 dopamine antagonist with Kis of 3.6, 10.1, 5147, and 7430 nM for rD4-Dopamine, hD4.2-Dopamine, rD2-Dopamine, and Histamine-H1 receptors, respectively .
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Cat. No.: HY-14782
CAS No.: 222551-17-9
Purity:  98.60%
Synonyms: SLV313
Research Areas:  

Neurological Disease

Adoprazine (SLV313) is a full 5-HT1A receptor agonist with a pEC50 of 9 at cloned h5-HT1A receptors. Adoprazine (SLV313) is a full D2 and D3 receptor antagonist with pA2s of 9.3 and 8.9 at hD2 and hD3 receptors, respectively. Adoprazine (SLV313) has the characteristics of atypical antipsychotics .
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Cat. No.: HY-101065
CAS No.: 85378-82-1
Purity:  98.55%
Synonyms: (+)-AJ 76 hydrochloride; (1S,2R)-AJ 76 hydrochloride
Target:  

Dopamine Receptor

Research Areas:  

Others

AJ-76 hydrochloride ((+)-AJ 76 hydrochloride) is an antagonist of dopamine autoreceptor with pKi values of 6.95, 6.67, 6.37, 6.21 and 6.07 for hD3, hD4, hD2S, hD2L and rD2 receptors, respectively.
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Cat. No.: HY-W022404
CAS No.: 174096-41-4
Research Areas:  

Others

H-D-4-Pal-OH.2HCl is an alanine derivative .
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Cat. No.: HY-47822
CAS No.: 851873-40-0
Target:  

Sirtuin

Research Areas:  

Neurological Disease

WAY-354574 is an active molecule targeting deacetylase (Sirtuin) for the study of Huntington's disease (HD) .
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Cat. No.: HY-Y0315S
CAS No.: 97135-07-4
Synonyms: 2,5-HD-d10
2,5-Hexanedione-d10 (2,5-HD-d10) is the deuterium labeled 2,5-Hexanedione. Hexane-2,5-dione (2,5-HD) is an orally active, CNS-penetrant cytotoxic agent . Hexane-2,5-dione reduces BCL-2 and β-catenin/TCF transcriptional activity, increases BAX and active caspase-3 expression, and promotes apoptosis. Hexane-2,5-dione causes an accumulation of neurofilaments within axons in rats. Hexane-2,5-dione can be used for the research of neurodegenerative diseases .
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Cat. No.: HY-155397
CAS No.: 3126555-89-0
Target:  

PROTACs HDAC

Research Areas:  

Cancer

PRO-HD2 is a HDAC6 PROTAC degrader. PRO-HD2 exerts antiproliferative activity in leukemia cells. PRO-HD2 can be used for leukemia research .
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Cat. No.: HY-155398
CAS No.: 3126555-94-7
Research Areas:  

Cancer

PRO-HD3 is a HDAC6 PROTAC degrader. PRO-HD3 exerts antiproliferative activity in leukemia cells. PRO-HD3 can be used for leukemia research .
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Cat. No.: HY-155396
CAS No.: 3126555-99-2
Target:  

PROTACs HDAC

Research Areas:  

Cancer

PRO-HD1 is a PROTAC HDAC6 degrader. PRO-HD1 degrades HDAC6 in A549 cells, and inhibits proliferation of Jurkat cells (IC50: 5.8 μM) .
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Cat. No.: HY-N10398
CAS No.: 1008376-90-6
Garcinielliptone HD is a compound isolated from the heartwood of Garcinia subelliptica Merr. .
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Cat. No.: HY-P5790
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

μ-TRTX-Hd1a, a spider venom, is a selective NaV 1.7 inhibitor. μ-TRTX-Hd1a is a gating modifier that inhibits human NaV 1.7 by interacting with the S3b-S4 paddle motif in channel domain II .
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Cat. No.: HY-RS24494
Research Areas:  

Others

Htt Rat Pre-designed siRNA Set A contains three designed siRNAs for Htt gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS06490
Research Areas:  

Others

HTT Human Pre-designed siRNA Set A contains three designed siRNAs for HTT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-B0274AS
Chlorprothixene-d6 hydrochloride is the deuterium labeled Chlorprothixene hydrochloride. Chlorprothixene hydrochloride is a dopamine and histamine receptors antagonist with Kis of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively. Antipsychotic activity .
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Cat. No.: HY-B0274AR
CAS No.: 6469-93-8
Chlorprothixene (hydrochloride) (Standard) is the analytical standard of Chlorprothixene (hydrochloride). This product is intended for research and analytical applications. Chlorprothixene hydrochloride is a dopamine and histamine receptors antagonist with Kis of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively. Antipsychotic activity .
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Cat. No.: HY-B0274R
CAS No.: 113-59-7
Chlorprothixene (Standard) is the analytical standard of Chlorprothixene. This product is intended for research and analytical applications. Chlorprothixene is a dopamine and histamine receptors antagonist with Kis of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively. Antipsychotic activity .
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Cat. No.: HY-W008269R
CAS No.: 76985-09-6
Research Areas:  

Others

H-D-2-Nal-OH (Standard) is the analytical standard of H-D-2-Nal-OH. This product is intended for research and analytical applications. H-D-2-Nal-OH is an alanine derivative .
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