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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
538 Results for "
Homo sapiens complement 5
" in MedChemExpress (MCE) Product Catalog:
Products (538)
538 Results for "Homo sapiens complement 5" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-P1036
CAS No.: 206645-99-0
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3
3 Cited Publications
Cat. No.: HY-P1036A
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2
2 Cited Publications
Cat. No.: HY-P3252A
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2
2 Cited Publications
Cat. No.: HY-N9481
CAS No.: 56411-57-5
2
2 Cited Publications
Cat. No.: HY-P1345A
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2
2 Cited Publications
Synonyms: ALXN2050; ACH 0145228; ACH-5228
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Vemircopan (ALXN2050) is an orally active complement factor D (FD) inhibitor. Vemircopan can be used in the research of diseases such as myasthenia gravis, lupus nephritis, IgA nephropathy, and paroxysmal nocturnal hemoglobinuria .
2
2 Cited Publications
Cat. No.: HY-P70485
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: VTN; Vitronectin; VN; Serum Spreading Factor; Serum-Spreading Factor; complement S-Protein; Somatomedin B; S-Protein; V75; Vitronectin (Serum Spreading Factor, Somatomedin B, complement S-Protein); Epibolin; VNT
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-A0183
CAS No.: 1446756-47-3
Synonyms: Phospholipids, phosphatidylserines; Serine glycerophosphatides
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1
1 Cited Publications
Homo-PROTAC cereblon degrader 1 is a highly selective cereblon (CRBN) PROTAC degrader. Homo-PROTAC cereblon degrader 1 induces self-directed ubiquitination and proteasomal degradation of CRBN. Homo-PROTAC cereblon degrader 1 blocks Pomalidomide (HY-10984)-induced degradation of IKZF1 and IKZF3. Homo-PROTAC cereblon degrader 1 antagonizes the growth inhibitory effect of Pomalidomide on multiple myeloma cells. Homo-PROTAC cereblon degrader 1 can be used in studies related to multiple myeloma .
1
1 Cited Publications
Homo-PROTAC pVHL30 degrader 1 is a Homo-PROTAC autodegraders targeting the von Hippel-Lindau E3 ubiquitin ligase (VHL), with Kd values of 11 nM and 25 nM for pVHL19-EloBC and pVHL30-EloBC, respectively. Homo-PROTAC pVHL30 degrader 1 induces Cullin2 depletion, promotes VHL dimerization to form a ternary complex, and drives proteasome-dependent and CRL2-VHL-like ubiquitination-dependent autodegradation. Homo-PROTAC pVHL30 degrader 1 does not trigger hypoxic responses, and only causes extremely mild stabilization of hypoxia-inducible factor α subunits. Homo-PROTAC pVHL30 degrader 1 can be used in studies related to cervical cancer and osteosarcoma .
1
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1
1 Cited Publications
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Complement C5-IN-1 is a Complement C5 inhibitor with an IC50 of less than 0.005 μM in serum inhibition assays. Complement C5-IN-1 stabilizes the α-helical conformation, thereby burying the cleavage site and preventing cleavage of C5 by C5 convertase. Complement C5-IN-1 inhibits membrane attack complex deposition in human serum and whole blood complement activation assays. Complement C5-IN-1 can be used in research related to complement-mediated diseases, such as paroxysmal nocturnal hemoglobinuria .
1
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1
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3-Phenoxybenzaldehyde has weak complement classical pathway inhibition and hemolytic activity .
1
1
1 Cited Publications
Cat. No.: HY-P75464
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C1QB; complement Subcomponent C1q Chain B; complement C1q B Chain; complement C1q Chain B; complement Component 1, Q Subcomponent, Beta Polypeptide; complement Component C1q, B Chain; complement Component 1, Q Subcomponent, B Chain; C1QD2; complement C1q
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-P81185
Synonyms: C5; C6; C7; C8; C9; complement component 5; complement component 6; complement component 7; complement component 8; complement component 9; MAC; Membrane attack complex; TCC; Terminal complement complex.
1
1 Cited Publications
Cat. No.: HY-P71718
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C1QA; complement Component 1, Q Subcomponent, A Chain; complement C1q A Chain; complement C1q Chain A; complement C1q Subcomponent Subunit A; complement Component C1q, A Chain; complement Component 1, Q Subcomponent, Alpha Polypeptide; C1QD1
Species:
Mouse
Source:
P. pastoris
1
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Research Areas:
1
1 Cited Publications
Cat. No.: HY-P70101
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CLEC7A; CDNA FLJ59887, Moderately Similar To Homo sapiens C-Type Lectin Domain Family 7, Member A (CLEC7A), Transcript Variant 4, MRNA; Prev. CLECSF12; C-Type Lectin Domain Containing 7A Transcript Variant 7; C-Type Lectin Domain Family 7 Member A; C-Type
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
