210 Results for "

MGL

" in MedChemExpress (MCE) Product Catalog:
Products (210)

210 Results for "MGL" in MCE Product Catalog:

Cat. No.: HY-119033
CAS No.: 1881244-28-5
Purity:  98.65%
Target:  

MAGL

Research Areas:  

Inflammation/Immunology

MGL-IN-1 is a potent and selective irreversible MGL (β-lactam-based monoacylglycerol lipase) inhibitor. MGL-IN-1 alleviates symptoms in a MS model in vivo and exhibits analgesic effects in an acute inflammatory pain model in vivo. MGL-IN-1 displays high membrane permeability and brain penetrant .
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Cat. No.: HY-100792
CAS No.: 565460-15-3
Purity:  99.74%
Target:  

Bacterial

Research Areas:  

Cancer

URB602 is a selective monoacylglycerol lipase (MGL) inhibitor, which inhibits rat brain MGL with IC50 of 28±4 μM through a noncompetitive mechanism.
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Cat. No.: HY-N2417
CAS No.: 13832-70-7
Stearyl glycyrrhetinate, a major component in licorice extract, has a MIC against S. aureus strains of more than 256 mg/L. Stearyl glycyrrhetinate has antibacterial effects .
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Cat. No.: HY-167887
CAS No.: 2894124-00-4
Target:  

Endogenous Metabolite

Research Areas:  

Infection

7PPD-Q is a substituted p-phenylenediamine antioxidants derivatives. 7PPD-Q has toxic to the bacterium V. fischeri (EC50 = 14.9 mg/L) .
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Cat. No.: HY-117089
CAS No.: 112281-77-3
Purity:  96.98%
Research Areas:  

Infection

Tetraconazole is a selective irreversible inhibitor of 14-α-sterol demethylase (CYP51) with antifungal activity. Tetraconazole competitively binds to the enzyme to block fungal ergosterol synthesis, resulting in cell membrane damage. The EC50 of tetraconazole against wheat pathogens is 0.382-0.802 mg/L, and the EC50 against onion root tip meristem cell growth is 6.7 mg/L, and (R)-(+)-Tetraconazole is 1.49-1.98 times more active than (S)-(-)-Tetraconazole. Tetraconazole can also induce oxidative stress and chromosomal aberrations in plant cells .
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Cat. No.: HY-118653
CAS No.: 1221418-42-3
Target:  

MAGL

Research Areas:  

Metabolic Disease

SAR629 is a potent monoglyceride lipase (MGL) covalent inhibitor. SAR629 also inhibits 2-Arachidonoylglycerol (2-AG) degradation .
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Cat. No.: HY-118158
CAS No.: 256383-45-6
Purity:  99.83%
Target:  

FAAH

Research Areas:  

Neurological Disease

FAAH/MAGL-IN-4 (Compound 13) is a potent fatty acid amide hydrolase (FAAH) and monoglyceride lipase (MGL) inhibitor with IC50s of 9.1 nM and 7.9 μM, respectively. FAAH/MAGL-IN-4 can be used for the research of pain and CNS disorders .
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Cat. No.: HY-151600
CAS No.: 2757552-21-7
Purity:  99.83%
Target:  

Transketolase

Research Areas:  

Others

Transketolase-IN-2 (compound 4w) is a potent Transketolase inhibitor. Transketolase-IN-2 shows strong inhibition of Digitaria sanguinalis and Amaranthus retroflexus (over 90% at 200 mg/L and about 80% at 100 mg/L). Transketolase-IN-2 can be used in studies of weed control .
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Cat. No.: HY-N11654
CAS No.: 22910-86-7
Synonyms: Cardol monoene
Bilobol is a potent insecticide against Aedes aegypti with a LC50 of 7.67 mg/L. Bilobol also has antitumor activity .
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Cat. No.: HY-U00249
CAS No.: 110588-57-3
Synonyms: R66905
Target:  

Fungal

Research Areas:  

Infection

Saperconazole (R66905) is a broad-spectrum antifungal triazole and has potent activity against Aspergillus with an MIC90 of 0.19 mg/L.
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Cat. No.: HY-137898
CAS No.: 69787-79-7
Avilamycin A is an oral active antibiotic. Avilamycin A is active against veterinary isolates of C. perfringens (MICs ≤ 0.06-0.5 mg/L) and B. hyodysenteriae (MICs = 12.5-100 μg/ml) .
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Cat. No.: HY-RS18435
Research Areas:  

Others

Clec10a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Clec10a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-N0313R
CAS No.: 514-47-6
Euphol (Standard) is the analytical standard of Euphol. This product is intended for research and analytical applications. Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active. Euphol inhibits the monoacylglycerol lipase (MGL) activity via a reversible mechanism (IC50=315 nM). MGL inhibition in the periphery modulates the endocannabinoid system to block the development of inflammatory pain .
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Cat. No.: HY-114689
CAS No.: 15307-78-5
Purity:  ≥97.0%
Target:  

Drug Metabolite

Research Areas:  

Inflammation/Immunology

Diclofenac methyl ester is a metabolite of Diclofenac (HY-15036), which exhibits acute cytotoxicity with a LC50 of 0.5 mg/L in H. azteca .
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Cat. No.: HY-59320
CAS No.: 3973-08-8
4-Thiazolecarboxylic acid (Compound 1e) is an intermediate. 4-Thiazolecarboxylic acid can be used in the synthesis of MGL-IN-2 (HY-177534). MGL-IN-2 inhibits wild-type MGL enzyme activity with an IC50 of 0.0121 μM. 4-Thiazolecarboxylic acid can be used in the research of metabolic diseases .
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Cat. No.: HY-Y1826
CAS No.: 92-55-7
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

IITR01324 is an antimicrobial agent. IITR01324 has antimicrobial activity against Escherichia coli (MIC = 3.58 mg/L) and other Gram-negative bacteria (Shigella flexneri: MIC = 3.58 mg/L; Cronobacter sakazakii: MIC = 28.63 mg/L). IITR01324 exerts its antimicrobial activity by destroying bacterial DNA after activation of intracellular reductases. IITR01324 can be used to study the development of new antimicrobial drugs, especially against multidrug-resistant (MDR) pathogens .
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Cat. No.: HY-123652
CAS No.: 25287-60-9
Target:  

Parasite

Research Areas:  

Infection

Etofamide is an antimicrobial agent with IC50 value of 5.96 mg/L against amoeba .
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Cat. No.: HY-W010235
CAS No.: 4179-19-5
Category:  

Natural Products

Target:  

Drug Derivative

3,5-Dimethoxytoluene, a methylated phenolic derivative, is one of characteristic scent compounds emitted from flowers of most rose varieties. 3,5-Dimethoxytoluene shows significant fumigant toxicity against L. serricorne and L. bostrychophila with LC50 values of 4.99 mg/L air and 0.91 mg/L air, respectively .
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Cat. No.: HY-122298
CAS No.: 517875-34-2
Synonyms: XDE 777
Target:  

Antibiotic Fungal

Research Areas:  

Infection

Fenpicoxamid is a new fungicide. Fenpicoxamid inhibits the growth of the fungus Z. tritici with an EC50 value of 0.051 mg/L .
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Cat. No.: HY-Y1667R
CAS No.: 608-33-3
2,6-Dibromophenol (2,6-DBP) is a weak inhibitor targeting voltage-gated Ca2+ channels. 2,6-Dibromophenol has no significant effect on potassium-induced calcium elevation in PC12 cells. 2,6-Dibromophenol shows a 48 h EC50 of 2.78 mg/L for Daphnia magna and a 96 h EC50 of 9.90 mg/L for algae (Scenedesmus quadricauda) .
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