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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
150 Results for "
MMP1
" in MedChemExpress (MCE) Product Catalog:
Products (150)
150 Results for "MMP1" in MCE Product Catalog:
2
2
2 Cited Publications
Cat. No.: HY-P4931
CAS No.: 720710-69-0
2
2 Cited Publications
Cat. No.: HY-19485
CAS No.: 1224964-36-6
Target:
Research Areas:
XL-784 is a selective matrix metalloproteinases (MMP) inhibitor, with IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, MMP-13, respectively.
2
2
Category:
other families Coumarins Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology
Target:
1
1
1 Cited Publications
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PD-166793 is a potent, selective, orally active and wide-broad spectrum inhibitor of MMP, exhibiting nanomolar potency against MMP-2, MMP-3 and MMP-13 (IC50=4, 7, and 8 nM, respectively) and micromolar potency vs MMP-1, -7 and -9 (IC50=6.0, 7.2, and 7.9 μM, respectively). PD-166793 can attenuate left ventricular remodeling and dysfunction in a rat model of progressive heart failure [1] .
1
1
1 Cited Publications
Cat. No.: HY-W011085
CAS No.: 210755-45-6
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CP-471474 is an orally active and pan MMP inhibitor, with IC50 values of 1170 nM (MMP-1), 0.7 nM (MMP-2), 16 nM (MMP-3), 13 nM (MMP-9) and 0.9 nM (MMP-13), respectively [1] .
1
1 Cited Publications
Cat. No.: HY-P70250
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MMP1; Matrix Metallopeptidase 1 (Interstitial Collagenase); Prev. CLG; Matrix Metalloproteinase 1; Interstitial Collagenase; Matrix Metalloprotease 1; Fibroblast Collagenase; Alternative Protein MMP1; Matrix Metalloproteinase 1 (Interstitial Collagenase); MMP-1; Matrix Metallopeptidase 1; Matrix Metalloproteinase-1
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-W127716
CAS No.: 136724-73-7
Cat. No.: HY-N3387
CAS No.: 30508-27-1
Cat. No.: HY-P2179
CAS No.: 150956-92-6
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Cat. No.: HY-164159
CAS No.: 130603-71-3
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Research Areas:
α-Glucosylrutin, a flavonoid, is a potent antioxidant with free radical scavenging activity. α-Glucosylrutin reduces MMP-1 gene expression, protein expression, and enzyme activity, and reduces MMP-2 protein expression and enzyme activity in UVA-irradiated human dermal fibroblasts. α-Glucosylrutin prevents oxidative stress-induced intracellular tyrosine residue phosphorylation and counteracts intracellular thiol level depletion in human skin cells. α-Glucosylrutin is effective in the prevention of dermatologic diseases in which oxidative stress is of pathogenetic relevance, e.g. in polymorphous light eruption (PLE). α-Glucosylrutin can be used for the research of UV-induced skin photodamage/photoaging [1] .
Cat. No.: HY-124029
CAS No.: 1222173-37-6
Synonyms: MMP13-IN-3
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Research Areas:
BI-4394 (MMP13-IN-3), a chemical probe, is a potent, selective, and orally active MMP-13 inhibitor (IC50=1 nM [1]) for the potential treatment of osteoarthritis . BI-4394 is >1000 selective over other MMPs .
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UK-370106 is a potent and highly selective MMP-3 (IC50 of 23 nM) and MMP-12 (IC50 of 42 nM) inhibitor with >1200-fold higher potency than MMP-1, MMP-2, MMP-9, and MMP-14, and about 100-fold than MMP-13 and MMP-8. UK-370106 potently inhibits cleavage of [ 3H]-fibronectin by MMP-3 (IC50 of 320 nM) and has little effect on keratinocyte migration in vitro [1] .
Cat. No.: HY-P10043
CAS No.: 150956-93-7
Cat. No.: HY-N1981S1
CAS No.: 60892-83-3
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Cat. No.: HY-177590
CAS No.: 919751-10-3
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Research Areas:
14-3-3-IN-2 is a 14-3-3 protein inhibitor with an IC50 of 15 nM. 14-3-3-IN-2 can disrupt the interaction of 14-3-3α with aminopeptidase N and down-regulate 14-3-3α increased MMP-1 mRNA levels [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
