Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
40 Results for "
NRTI
" in MedChemExpress (MCE) Product Catalog:
Products (40)
40 Results for "NRTI" in MCE Product Catalog:
Cat. No.: HY-17423S
CAS No.: 1260619-56-4
Cat. No.: HY-17427S
CAS No.: 2714436-53-8
Synonyms: BW1592-15N,d2
Cat. No.: HY-B0250A
CAS No.: 173522-96-8
Synonyms: BCH-189 salicylate
Target:
Lamivudine (BCH-189) salicylate is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine salicylate can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS .
Cat. No.: HY-17427S2
CAS No.: 1217820-69-3
Synonyms: BW1592-13C,15N2
Cat. No.: HY-14266R
CAS No.: 244767-67-7
Synonyms: TMC120 (Standard); R147681 (Standard)
Research Areas:
Dapivirine (Standard) is the analytical standard of Dapivirine. This product is intended for research and analytical applications. Dapivirine (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI). Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations .
Cat. No.: HY-12108
CAS No.: 280571-30-4
Target:
Research Areas:
S 1360 is a potent and selective inhibitor of HIV-1 integrase. S 1360 inhibits the catalytic activity of purified integrase (
IC50: 20 nM). The EC50, and CC50 of S 1360
in MTT assay (MT-4 cells infected with HIV-1 IIIB) are 200 nM and 12 μM, respectively. S 1360 has antiviral activity against both X4 tropic and R5 tropic strains, as well as NRTI, NNRTI and PI drug-resistant variants .
Cat. No.: HY-126781
CAS No.: 141790-23-0
Synonyms: BM-211290
Target:
Research Areas:
Fozivudine tidoxil (BM-211290) is an orally active thioether lipid-zidovudine (ZDV) conjugate with anti-HIV activity. Fozivudine tidoxil, a member of the NRTI family of agent, is incorporated into the newly synthesized strand of DNA during intracellular viral replication and irreversibly binds viral RT which disrupts viral reverse-transcription . Fozivudine tidoxil is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-17427S4
Synonyms: BW1592-d2
Cat. No.: HY-135330
CAS No.: 1391052-30-4
Cat. No.: HY-14922
CAS No.: 763903-67-9
Target:
Research Areas:
Fosalvudine tidoxil is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Fosalvudine tidoxil is a prodrug derived from Alovudine (HY-B1516). Fosalvudine tidoxil is less toxic than Alovudine and can be used for the research of HIV-1 infection .
Cat. No.: HY-19314R
CAS No.: 1011529-10-4
Synonyms: RO-0622 (Standard); FNC (Standard)
Research Areas:
Azvudine (Standard) is the analytical standard of Azvudine. This product is intended for research and analytical applications. Azvudine (RO-0622) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine exerts highly potent inhibition on HIV-1 (EC50s ranging from 0.03 to 6.92 nM) and HIV-2 (EC50s ranging from 0.018 to 0.025 nM). Azvudine inhibits NRTI-resistant viral strains . Azvudine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-14266S
CAS No.: 1329613-10-6
Synonyms: TMC120-d11; R147681-d11
Cat. No.: HY-W654247
CAS No.: 2714473-70-6
Cat. No.: HY-B0250S
Synonyms: BCH-189-15N,d2
Cat. No.: HY-14266S1
CAS No.: 1309283-15-5
Synonyms: TMC120-d4; R147681-d4
Cat. No.: HY-B0116S
CAS No.: 1219803-67-4
Cat. No.: HY-B0250S2
CAS No.: 1261394-64-2
Synonyms: BCH-189-13C,15N3
Cat. No.: HY-139262A
Target:
Research Areas:
FNC-TP trisodium is the intracellular active form of FNC. FNC is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV . FNC-TP (trisodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-B0250S1
Synonyms: BCH-189-13C,15N2,d2
Cat. No.: HY-137522AS1
Synonyms: 3'-Azido-3'-deoxythymidine β-D-glucuronide-13C6
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
