Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
90 Results for "
PP1
" in MedChemExpress (MCE) Product Catalog:
Products (90)
90 Results for "PP1" in MCE Product Catalog:
Target:
Research Areas:
3BrB-PP1 is an ATP-competitive analog. 3BrB-PP1 can specifically inhibit the activity of protein kinase with mutations in the ATP-binding pocket (mutation of Thr97 within Sty1’s ATP-binding pocket) [1] .
Cat. No.: HY-131368A
CAS No.: 4484-88-2
Synonyms: Tre6P
Target:
Cat. No.: HY-172307
CAS No.: 2089461-53-8
Target:
Research Areas:
m7(3'OMeG)(5')pp-1-imidazol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Cat. No.: HY-P12012
CAS No.: 870274-84-3
Research Areas:
PP1 peptide is an antagonist that specifically binds to scavenger receptor AI (SR-AI), with an IC50 of 29 μM against bovine SR-AI. By recognizing SR-AI which is highly expressed on macrophages, PP1 peptide enables precise targeting and internalization of inflammatory regions within atherosclerotic plaques. PP1 peptide can be used in research related to atherosclerosis [1].
Cat. No.: HY-P11336
CAS No.: 365400-08-4
Target:
Research Areas:
Cat. No.: HY-172708
Target:
Research Areas:
DSPE-PEG2000-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG2000-PP1 can be used for drug delivery [1].
Cat. No.: HY-172708A
Target:
Research Areas:
DSPE-PEG3400-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG3400-PP1 can be used for drug delivery [1].
Cat. No.: HY-137135
CAS No.: 28874-45-5
Cantharidic acid is a selective inhibitor for protein phosphatase 2 (PP2A) and protein phosphatase 1 (PP1). Cantharidic acid inhibits cell viability and arrest cell cycle at sub G1 phase, induces apoptosis in cells NPC-39 and HONE-1 through the upregulation of ERK1/2, p38, and JNK1/2 pathway [1].
Research Areas:
2-Methyl-3-buten-1-ol is a pharmaceutical intermediate that can be used in organic synthesis-related research. 2-Methyl-3-buten-1-ol can serve as a precursor of 2-methyl-3-butenyl-1-pyrophosphate (2M3B1PP) .
Cat. No.: HY-P11336A
Target:
Research Areas:
Cat. No.: HY-172707
Target:
Research Areas:
DSPE-PEG1000-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG1000-PP1 can be used for drug delivery [1].
Cat. No.: HY-172709
Target:
Research Areas:
DSPE-PEG5000-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG5000-PP1 can be used for drug delivery [1].
Cat. No.: HY-102069R
CAS No.: 956025-83-5
Research Areas:
3MB-PP1 (Standard) is the analytical standard of 3MB-PP1 (HY-102069). This product is intended for research and analytical applications. 3MB-PP1, a bulky purine analog, is a Polo-like kinase 1 (Plk1) inhibitor. 3MB-PP1 blocks mitotic progression and cell division arise through target Plk1 in in cells expressing analog-sensitive Plk1 alleles. 3MB-PP1 specifically inhibits the activity of analog-sensitive Ssn3 (Cdk8). 3MB-PP1 inhibits Leu93 Mutant Zipper-interacting protein kinase (Leu93-ZIPK; IC50=2 μM). 3MB-PP1 can be used for the research of hypha formation of Candida albicans and cell division [1] .
Cat. No.: HY-113976AR
CAS No.: 145-73-3
Synonyms: Endothal (Standard)
Target:
Research Areas:
Endothall (Standard) is the analytical standard of Endothall. This product is intended for research and analytical applications. Endothall (Endothal) is a protein phosphatase 2A (PP2A) inhibitor with IC50s of 90 nM and 5 µM for PP2A and PP1, respectively. Endothall can be used as an herbicide. Endothall also is useful in cancer chemotherapy [1].
Cat. No.: HY-187407A
Synonyms: DOPE-PEG2000-Mal-Cys-LSLERFLRCWSDAPA
Target:
Research Areas:
DOPE-PEG2000-PP1 (DOPE-PEG2000-Mal-Cys-LSLERFLRCWSDAPA) is an amphiphilic lipid-PEG-peptide conjugate consisting of DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine), PEG2000, and the PP1 peptide. PP1 peptide functions as a targeting ligand for specific cell or tissue recognition. DOPE-PEG2000-PP1 is used for targeted drug delivery through functionalization of liposomes and lipid nanoparticles.
Cat. No.: HY-187905A
Synonyms: DMG-PEG2000-Mal-Cys-LSLERFLRCWSDAPA
Target:
Research Areas:
DMG-PEG2000-PP1 (DMG-PEG2000-Mal-Cys-LSLERFLRCWSDAPA) is a functionalized PEGylated phospholipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and a PP1 (HY-P12012) peptide as a terminal targeting/functional ligand. DMG-PEG2000-PP1 can be used in research on targeted drug delivery for atherosclerosis [1].
Cat. No.: HY-189161A
Synonyms: DSG-PEG2000-Mal-Cys-LSLERFLRCWSDAPA
Target:
Research Areas:
DSG-PEG2000-PP1 (DSG-PEG2000-Mal-Cys-LSLERFLRCWSDAPA) is a functionalized PEGylated phospholipid conjugate composed of three modular components: distearoylglycerol (DSG) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and a PP1 (HY-P12012) peptide as a terminal targeting/functional ligand. DSG-PEG2000-PP1 can be used in research on targeted drug delivery for atherosclerosis [1].
Cat. No.: HY-108599R
CAS No.: 28399-31-7
Synonyms: FR236924 (Standard)
Target:
Research Areas:
DCP-LA (Standard) is the analytical standard of DCP-LA. This product is intended for research and analytical applications. DCP-LA (FR236924), a linoleic acid derivative, selectively and directly activates PKCε. DCP-LA activates Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) and inhibits protein phosphatase-1 (PP-1) to stimulate AMPA receptor exocytosis. DCP-LA inhibits activation of caspase-3/-9 and protects neurons at least in part from oxidative stress-induced apoptosis[1][2][3].
Cat. No.: HY-187749A
Synonyms: DPPE-PEG2000-Mal-Cys-LSLERFLRCWSDAPA
Target:
Research Areas:
DPPE-PEG2000-PP1 (DPPE-PEG2000-Mal-Cys-LSLERFLRCWSDAPA) is a functionalized PEGylated phospholipid conjugate composed of three modular components: 1,2-dipalmitoyl-sn-glycerol-3-phosphate ethanolamine (DPPE) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and a PP1 (HY-P12012) peptide as a terminal targeting/functional ligand. DPPE-PEG2000-PP1 can be used in research on targeted drug delivery for atherosclerosis [1].
Cat. No.: HY-125258
CAS No.: 752216-12-9
Target:
Research Areas:
EBOV-IN-11 is a protein phosphatase 1 (PP1) inhibitor, with Kd values of 1.88 nM and 8.01 nM against wild-type and quadruple-mutant PP1, respectively. EBOV-IN-11 potently inhibits the replication and transcription of EBOV-eGFP virus. EBOV-IN-11 can be used in studies related to Ebola virus infection [1].
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
