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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
ewing
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "ewing" in MCE Product Catalog:
Cat. No.: HY-P87023
Synonyms: ETS-domain transcription factor antibody; FEV (ETS oncogene family) antibody; FEV antibody; FEV ETS transcription factor antibody; FEV_HUMAN antibody; Fifth ewing sarcoma variant antibody; Fifth ewing variant protein antibody; HSRNAFEV antibody; mPet1 antibody; PC12 ETS domain-containing transcription factor 1 antibody; ETS-domain transcription factor antibody; FEV (ETS oncogene family) antibody; FEV antibody; FEV ETS transcription factor antibody; FEV_HUMAN antibody; Fifth ewing sarcoma variant antibody; Fifth ewing variant protein antibody; HSRNAFEV antibody; mPet1 antibody; PC12 ETS domain-containing transcription factor 1 antibody; PC12 ETS factor 1 antibody; Pet-1 antibody; Protein FEV antibody;
Cat. No.: HY-183755
Target:
Research Areas:
YSA64 is an orally active RBM39-targeting molecular glue. YSA64 promotes degradation via formation of a DCAF15/DDB1 ternary complex, dependent on Cullin-RING E3 ligase and proteasome activity. YSA64 can be used for the research of acute myeloid leukemia and Ewing sarcoma .
Cat. No.: HY-W009929
CAS No.: 18979-55-0
Synonyms: 4-(Hexyloxy)phenol
AC-45594 (4-(Hexyloxy)phenol) is a UPR activator. AC-45594 induces endoplasmic reticulum stress, activates the unfolded protein response (UPR), and drives the transition from adaptive stress signaling to terminal stress signaling, ultimately leading to cell Apoptosis. AC-45594 activates Caspase-3, induces PARP cleavage, and increases the protein level of DR5. AC-45594 selectively inhibits the growth of Ewing sarcoma cells .
Cat. No.: HY-103713AR
CAS No.: 2044953-70-8
Synonyms: SP-2577 mesylate (Standard)
Research Areas:
Seclidemstat mesylate (Standard) is the analytical standard of Seclidemstat mesylate (HY-103713A). This product is intended for research and analytical applications. Seclidemstat (SP-2577) mesylate is a potent noncompetitive and reversible KDM1A (LSD1) inhibitor (Ki=31 nM, IC50=13 nM). Seclidemstat mesylate promotes antitumor immunity in switch/sucrose nonfermentable (SWI/SNF) complex mutated ovarian cancer, as well as inhibit virus production, viral DNA replication, and late gene expression. Seclidemstat mesylate can be used for the research of Ewing Sarcoma .
Cat. No.: HY-103713R
CAS No.: 1423715-37-0
Synonyms: SP-2577 (Standard)
Research Areas:
Seclidemstat (Standard) is the analytical standard of Seclidemstat (HY-103713). This product is intended for research and analytical applications. Seclidemstat is a potent noncompetitive and reversible KDM1A (LSD1) inhibitor (Ki=31 nM, IC50=13 nM). Seclidemstat promotes antitumor immunity in switch/sucrose nonfermentable (SWI/SNF) complex mutated ovarian cancer, as well as inhibit virus production, viral DNA replication, and late gene expression. Seclidemstat can be used for the research of Ewing Sarcoma .
Cat. No.: HY-13062AR
CAS No.: 20830-81-3
Synonyms: Daunomycin (Standard); RP 13057 (Standard); Rubidomycin (Standard)
Category:
Cat. No.: HY-183077
Research Areas:
BRD4 degrader-7 (Compound ZZ1) is a CTLH-dependent BRD4 degrader and c-Glue with a DC50 of 489 nM. BRD4 degrader-7 converts to a sulfinic acid derivative inside cells, interacts with the basic pocket of YPEL5, mediates the bridging of BRD4 BD1 to the YPEL5 subunit of the CTLH E3 ubiquitin ligase, and thereby promotes the formation of a ternary complex. BRD4 degrader-7 can be used in research on Ewing's sarcoma and leukemia .
Cat. No.: HY-13062AS
Synonyms: Daunomycin-13C,d3 TFA); RP 13057-13C,d3 TFA; Rubidomycin-13C,d3 TFA
Cat. No.: HY-183858
CAS No.: 1964516-59-3
Target:
Research Areas:
NCATS-SM1440 is a glycolysis inhibitor and metabolic regulator that targets LDHA and LDHB (IC50=0.06 μM and 0.03 μM, respectively). Upon binding to LDHA, NCATS-SM1440 blocks the glycolysis pathway and reduces lactate production. NCATS-SM1440 drives the shift of pyruvate metabolism toward mitochondrial metabolism, effectively disrupting the dependence of cancer cells on aerobic glycolysis. NCATS-SM1440 can be widely used in research related to cancer, Ewing's sarcoma, and other related conditions .
Cat. No.: HY-P703126
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FLI1; Transcription Factor ERGB; Fli-1 Proto-Oncogene, ETS Transcription Factor; ewing Sarcoma Breakpoint Region 2; SIC-1; ERGB Transcription Factor; EWSR2; ERGB Transcription Fuctor; FLI-1; Proto-Oncogene Fli-1; Friend Leukemia Integration 1 Transcriptio
Species:
Human
Source:
E. coli
Cat. No.: HY-P703127
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: FLI1; Transcription Factor ERGB; Fli-1 Proto-Oncogene, ETS Transcription Factor; ewing Sarcoma Breakpoint Region 2; SIC-1; ERGB Transcription Factor; EWSR2; ERGB Transcription Fuctor; FLI-1; Proto-Oncogene Fli-1; Friend Leukemia Integration 1 Transcriptio
Species:
Human
Source:
E. coli
Cat. No.: HY-P75921
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MAP3K8; Proto-Oncogene Serine/Threoine Protein Kinase; Prev. ESTF; Cot (Cancer Osaka Thyroid) Oncogene; Prev. COT; Serine/Threonine-Protein Kinase Cot; Tumor Progression Locus 2; Cancer Osaka Thyroid Oncogene; Tpl-2; ewing Sarcoma Transformant; C-COT; AUR
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
