195 Results for "

outer

" in MedChemExpress (MCE) Product Catalog:
Products (195)

195 Results for "outer" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-128200
CAS No.: 108985-27-9
Purity:  99.84%
Synonyms: PQS
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

Pseudomonas quinolone signal (PQS) is a quorum-sensing signaling molecule produced by Pseudomonas aeruginosa. The synthesis of Pseudomonas quinolone signal relies on the las quorum-sensing system, and its biological activity is associated with the rhl system. Pseudomonas quinolone signal regulates the expression of the virulence gene lasB. Additionally, Pseudomonas quinolone signal plays roles in iron acquisition, cytotoxicity, outer-membrane vesicle biogenesis, and host immune modulation .
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2
2 Cited Publications
Cat. No.: HY-P80369
Synonyms: OMP2, VDAC1, YNL055C, N2441, YNL2441C, POR1, Non-selective voltage-gated ion channel 1, outer mitochondrial membrane protein porin 1, Voltage-dependent anion-selective channel protein 1, VDAC-1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, FC, IF-Tissue

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-128780B
CAS No.: 2408422-41-1
Purity:  99.74%
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

SPR206 acetate is a polymyxin analog with antibiotic activity against Gram-negative pathogens, including multidrug-resistant (MDR) variants. SPR206 acetate has an anti-bacterial infection effect by interacting with the bacterium’s outer membrane. The MIC values of SPR206 acetate against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301 are both 0.125 mg/L .
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1
1 Cited Publications
Cat. No.: HY-W008646
CAS No.: 6779-87-9
Synonyms: Dihydrobiopterin
7,8-Dihydro-L-biopterin is a NOS uncoupling inducer with blood-brain barrier permeability, and it is a reduced non-conjugated pteridine. 7,8-Dihydro-L-biopterin is the main metabolite of 4-amino-tetrahydro-L-biopterin, and it undergoes photooxidation to form biopterin. 7,8-Dihydro-L-biopterin promotes the conversion of nitric oxide synthase to a superoxide-producing form, thereby increasing oxidative stress levels in the renal outer medulla and inducing apoptosis. 7,8-Dihydro-L-biopterin is sensitive to the inhibitory effect of SOD, and it can be applied to research related to salt-sensitive hypertension, moderate to severe traumatic brain injury, and neurodegenerative diseases .
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1
1 Cited Publications
Cat. No.: HY-P71493
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ompA; Z1307; ECs1041; outer membrane protein A; outer membrane porin A
Species:  
E.coli
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P71494
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: outer membrane protein X; ompX; Z1036; ECs0892
Species:  
E.coli
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P86575
Synonyms: TOMM20; KIAA0016; Mitochondrial import receptor subunit TOM20 homolog; Mitochondrial 20 kDa outer membrane protein; outer mitochondrial membrane receptor Tom20

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-P2997
CAS No.: 9046-27-9
Synonyms: GGT, Porcine kidney
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

γ-glutamyltransferase, Porcine kidney (GGT, Porcine kidney) is an enzyme located on the outer surface of the cell membrane. γ-glutamyltransferase, Porcine kidney maintains the physiological concentration of cytoplasmic glutathione and the cell's defense against oxidative stress by cleaving extracellular glutathione and increasing the availability of amino acids. γ-glutamyltransferase, Porcine kidney is used for pancreatic cancer research .
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1
1 Cited Publications
Cat. No.: HY-118948
CAS No.: 1592908-75-2
Purity:  98.68%
Target:  

Bcl-2 Family

Research Areas:  

Neurological Disease

MSN-50 is a Bax and Bak oligomerization inhibitor. MSN-50 efficiently inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection .
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1
1 Cited Publications
Cat. No.: HY-D1056E
Synonyms: LPS, from Pseudomonas aeruginosa (10)
Lipopolysaccharides from P. aeruginosa (Pseudomonas aeruginosa) 10 are lipopolysaccharide endotoxins and TLR4 activators derived from Pseudomonas aeruginosa 10, and are classified as S-type LPS. Lipopolysaccharides from P. aeruginosa 10 exhibit a typical three-part structure: O-antigen, core oligosaccharide, and lipid A. The lipopolysaccharides of P. aeruginosa 10 have a fatty acid composition distinct from common enterobacteria, an exceptionally high degree of phosphorylation (triphosphate residues have been detected), and a unique outer region of the core oligosaccharide. Additionally, their O-specific side chains are typically rich in novel aminosugars. Lipopolysaccharides from P. aeruginosa 10 demonstrate susceptibility to viruses, with the level of susceptibility determined by the content of high molecular weight polysaccharides in their composition. The absence of high molecular weight polysaccharides increases their sensitivity to bacteriophages .
It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
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Cat. No.: HY-164036
CAS No.: 2930690-12-1
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Lolamicin is an orally effective inhibitor that specifically targets the Gram-negative bacteria lipoprotein transport system LolCDE complex. It selectively inhibits the transmembrane transport of outer membrane lipoproteins by competitively binding to lipoprotein binding sites. Lolamicin destroys the integrity of the bacterial outer membrane, leading to cell death, and has both bactericidal and antibacterial activity. It has significant effects on multidrug-resistant Enterobacteriaceae pathogens (such as Escherichia coli and Klebsiella pneumoniae). Lolamicin can be used to inhibit the study of acute pneumonia, sepsis and other infections caused by Gram-negative bacteria .
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Cat. No.: HY-W012669
CAS No.: 643-79-8
Synonyms: Phthaldialdehyde
Phthalaldehyde (Phthaldialdehyde) reacts with proteins containing primary amines and blocked amino-terminal peptides of amino acids. Phthalaldehyde stabilizes bacterial outer membranes and cell walls, increases the optical density of bacterial cell suspensions, and inhibits bacterial lysis induced by ethylenediaminetetraacetic acid and sodium dodecyl sulfate. Phthalaldehyde exhibits bactericidal activity against Gram-negative vegetative bacteria .
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Cat. No.: HY-136615
CAS No.: 71186-53-3
Purity:  ≥99.0%
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

5-Hydroxydecanoate sodium is a selective ATP-sensitive K + (KATP) channel blocker (IC50 of ~30 μM). 5-Hydroxydecanoate sodium is a substrate for mitochondrial outer membrane acyl-CoA synthetase and has antioxidant activity .
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Cat. No.: HY-E70306
Target:  

Parasite

Research Areas:  

Infection

Zymolyase, Arthrobacter luteus, is a zymolyase mainly found in Arthrobacter luteus. Enzyme, an enzyme with beta-1,3 glucanase activity, removes the electron-dense outer layer of the Plasmodium karinii cell wall, exposing an electron-lucent layer .
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Cat. No.: HY-P0311
CAS No.: 184776-51-0
Target:  

Bacterial

Research Areas:  

Infection

LAH4, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 possesses high plasmid DNA delivery capacities. LAH4 has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes .
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Cat. No.: HY-P5601
CAS No.: 214542-43-5
Target:  

Bacterial Fungal

Research Areas:  

Infection

Thanatin is an inducible cationic antimicrobial peptide. Thanatin is a pathogen-inducible single-disulfide-bond-containing β-hairpin AMP. Thanatin displays broad-spectrum activity against both Gram-negative and Gram-positive bacteria as well as against various species of fungi with MICs of 0.3-40 µM, 0.6-40 µM and 0.6-20 µM, respectively. Thanatin has the property of competitive replacement of divalent cations from bacterial outer membrane (OM), leading to OM disruption .
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Cat. No.: HY-P5601A
Target:  

Bacterial Fungal

Research Areas:  

Infection

Thanatin TFA is an inducible cationic antimicrobial peptide. Thanatin TFA s a pathogen-inducible single-disulfide-bond-containing β-hairpin AMP. Thanatin TFA displays broad-spectrum activity against both Gram-negative and Gram-positive bacteria as well as against various species of fungi with MICs of 0.3-40 µM, 0.6-40 µM and 0.6-20 µM, respectively. Thanatin TFA has the property of competitive replacement of divalent cations from bacterial outer membrane (OM), leading to OM disruption .
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Cat. No.: HY-A0089R
CAS No.: 1264-72-8
Synonyms: Polymyxin E sulfate (Standard)
Colistin (sulfate) (Standard) is the analytical standard of Colistin (sulfate). This product is intended for research and analytical applications. Colistin sulfate is a polypeptide antibiotic which inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria.
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Cat. No.: HY-125222
CAS No.: 2247733-08-8
Purity:  98.02%
Target:  

Dynamin

Research Areas:  

Others

Drp1-IN-1 is a dynamin-1-like protein (Drp1) inhibitor with an IC50 of 0.91 μM. Drp1 mediates the fission of the outer mitochondrial membrane. Drp1-IN-1 can be used to study diseases associated with mitochondrial dysfunction .
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Cat. No.: HY-P1632
CAS No.: 118231-04-2
Target:  

Bacterial

Research Areas:  

Infection Cancer

Tachyplesin I is a β-hairpin antimicrobial peptide that contains 17 amino acid residues. Tachyplesin I exhibits cytotoxic properties against various human tumor cell lines acting primarily by impairing the integrity of the outer cell membrane .
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