165 Results for "

Stimulating effect

" in MedChemExpress (MCE) Product Catalog:
Products (165)

165 Results for "Stimulating effect" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N0885
CAS No.: 472-26-4
Synonyms: Telobufotoxin; Telocinobufogenin
Telocinobufagin (Telobufotoxin; Telocinobufogenin) is an orally active bufadienolide with potential anti-tumor effects. Telocinobufagin exerts its anti-cancer effects on non-small cell carcinoma, osteosarcoma, thyroid cancer, breast cancer and head and neck squamous cell carcinoma by inhibiting the STAT3, JAK2/STAT3, LARP1-mTOR, PI3K/Akt/Snail and PLK1 pathways, and can also induce tumor cell apoptosis. Telocinobufagin enhances the Th1 immune response and protects against Salmonella typhimurium infection. Telocinobufagin has a strong cardiac-stimulating effect by inhibiting the activity of Na +/K +-ATPase, and it can promote renal fibrosis. Telocinobufagin demonstrates non-opioid analgesic effects in various acute pain models .
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Cat. No.: HY-137677B
CAS No.: 94825-44-2
Purity:  96.04%
Synonyms: Guanosine 5'-[γ-thio]triphosphate tetralithium
Target:  

GLUT

Research Areas:  

Metabolic Disease

GTPγS (Guanosine 5'-[γ-thio]triphosphate) tetralithium is a G-protein activator that protects proteins from proteolytic degradation, stimulates GLUT4 translocation in a tyrosine kinase-dependent manner, stimulate phospholipases and induce actin polymerization. GTPγS tetralithium to couple with G- protein α, to study its effect on kinase activity. GTPγS tetralithium acts as a component of lysis buffer .
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Cat. No.: HY-P3479
CAS No.: 12584-58-6
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Insulin (swine) is an orally active insulin derived from pigs. Insulin (swine) when administered orally acts as an antigen to reduce the severity of pancreatic lymphocyte infiltration, but has no metabolic effect on blood glucose levels. Insulin (swine) increases glucose oxidation, stimulates lipogenesis, and lowers blood glucose levels. Insulin (swine) can be used in diabetes research .
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Cat. No.: HY-128417
CAS No.: 492-62-6
Purity:  ≥98.0%
\alpha-D-glucose is a monosaccharide that has a more significant insulin stimulating effect than beta-D-glucose .
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Cat. No.: HY-119322
CAS No.: 279215-43-9
Purity:  ≥99.0%
Synonyms: NN414
Target:  

Potassium Channel

Research Areas:  

Metabolic Disease

Tifenazoxide (NN414) is a potent, orally active and SUR1/Kir6.2 selective K ATP channels opener. Tifenazoxide has antidiabetic effect, can inhibit glucose stimulated insulin release in vitro and in vivo, and has a beneficial effect on glucose homeostasis .
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Cat. No.: HY-Y0265
CAS No.: 91-56-5
Synonyms: Indoline-2,3-dione
Isatin (Indoline-2,3-dione) is a potent inhibitor of monoamine oxidase (MAO) with an IC50 of 3 μM. Also binds to central benzodiazepine receptors (IC50 against clonazepam, 123 μM) . Also acts as an antagonist of both atrial natriuretic peptide stimulated and nitric oxide-stimulated guanylate cyclase activity . Shows effect on the serotonergic system .
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Cat. No.: HY-109556
CAS No.: 169148-63-4
Target:  

Akt ERK

Research Areas:  

Metabolic Disease

Insulin Detemir is an artificial insulin, shows effect on controlling blood sugar levels. Insulin Detemir stimulates GLP-1 secretion as a consequence of enhanced Gcg expression by a mechanism involving activation of Akt- and/or extracellular signal-regulated kinase (ERK)-dependent-cat and CREB signaling pathways. Insulin Detemir can be used for type 2 diabetes research .
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Cat. No.: HY-N0614S
CAS No.: 1459161-55-7
Synonyms: E955-d6; Trichlorosucrose-d6
Sucralose-d6 is deuterium labeled Sucralose. Sucralose?(E955; Trichlorosucrose) is a?non-nutritive?artificial?sweetener and sugar substitute. Sucralose can activate a conserved neural fasting response and thereby exerts an appetite-stimulating effect in rodents .
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Cat. No.: HY-P3662
CAS No.: 82188-67-8
Target:  

Tyrosinase

Research Areas:  

Cancer

Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2 is a melanotropin, a melanocyte-stimulating hormone. Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2 stimulates tyrosinase and exhibits thermoregulatory effect in rats model .
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Cat. No.: HY-P5243
CAS No.: 767286-83-9
Synonyms: AHK-Cu
Research Areas:  

Others

Copper tripeptide-3 (AHK-Cu) is a bioactive peptide with promotion of hair growth effect. Copper tripeptide-3 increases dermal cell proliferation and viability while increasing the deposition of collagen to renew the extracellular matrix. Copper tripeptide-3 stimulates the elongation of human hair follicles and proliferation of dermal papilla cells .
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Cat. No.: HY-P5763
CAS No.: 1415039-77-8
Synonyms: PNX-20
Research Areas:  

Neurological Disease

Phoenixin-20 (PNX-20) is a bioactive peptide with hormone-like actions in vertebrates, and can stimulates hypothalamo-pituitary-gonadal hormones and regulate reproductive processes in mammals. Phoenixin-20 promotes neuronal mitochondrial biogenesis via CREB-PGC-1α pathway. Phoenixin-20 has anxiolytic effect .
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Cat. No.: HY-123335A
CAS No.: 2922280-21-3
Purity:  98.00%
Target:  

Somatostatin Receptor

Research Areas:  

Neurological Disease

L-796778 acetate is a selective agonist of the sst3 receptor. In CHO-K1 cells expressing the hsst3 receptor, L-796778 acetate is a partial agonist that inhibits Forskolin (HY-15371)-stimulated cAMP production with an IC50 value of 18 nM. L-796778 acetate has anticonvulsant effect .
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Cat. No.: HY-N2556
CAS No.: 514-46-5
Tirucallol, a tetracyclic triterpene, is isolated from Euphorbia lacteal latex. Tirucallol has topical anti-inflammatory effect. Tirucallol can suppress ear edema in the mouse model and inhibit nitrite production in lipopolysaccharide-stimulated macrophages .
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Cat. No.: HY-108278
CAS No.: 1222-57-7
Purity:  99.65%
Target:  

Drug Derivative

Research Areas:  

Endocrinology

Zolimidine, a derivate of imidazopyridine, is an orally active antiulcer agent. Zolimidine stimulates mucus secretion in intestinal mucosal cells and enhacnes intestinal wall more resistant to ulceration. Zolimidine exhibits gastroprotective effect in duodenal ulcer research .
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Cat. No.: HY-111029A
Purity:  99.83%
Target:  

GlyT

Research Areas:  

Others

ALX-1393 TFA, a selective GlyT2 inhibitor, has an antinociceptive effect on thermal, mechanical, and chemical stimulations in a rat acute pain model .
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Cat. No.: HY-N2495
CAS No.: 52250-35-8
Isomucronulatol is a flavonoid isolated from the roots of A. membranaceus. Isomucronulatol exhibits inhibitory effects on LPS-stimulated production IL-12 p40 in vitro and has potential anti-inflammatory effect .
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Cat. No.: HY-N0614R
CAS No.: 56038-13-2
Synonyms: E955 (Standard); Trichlorosucrose (Standard)
Research Areas:  

Cancer

Sucralose (Standard) is the analytical standard of Sucralose. This product is intended for research and analytical applications. Sucralose?(E955; Trichlorosucrose) is a?non-nutritive?artificial?sweetener and sugar substitute. Sucralose can activate a conserved neural fasting response and thereby exerts an appetite-stimulating effect in rodents .
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Cat. No.: HY-147071
CAS No.: 5634-86-6
Synonyms: DAPE
Target:  

Liposome

Research Areas:  

Metabolic Disease

1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine (DAPE) is a phospholipid phosphatidylethanolamine. Unlike other phospholipid phosphatidylethanolamines, 1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine has no significant effect on protein phosphatase PP2A activity and does not inhibit insulin-stimulated GLUT4 translocation .
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Cat. No.: HY-W040329R
CAS No.: 958-09-8
2'-Deoxyadenosine (Standard) is the analytical standard of 2'-Deoxyadenosine (HY-W040329). This product is intended for research and analytical applications. 2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer .
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Cat. No.: HY-111029
CAS No.: 949164-09-4
Target:  

GlyT

Research Areas:  

Neurological Disease

ALX-1393, a selective GlyT2 inhibitor, has an antinociceptive effect on thermal, mechanical, and chemical stimulations in a rat acute pain model .
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