1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. GlyT
  3. ALX-1393

ALX-1393 

Cat. No.: HY-111029
Handling Instructions

ALX-1393, a selective GlyT2 inhibitor, has an antinociceptive effect on thermal, mechanical, and chemical stimulations in a rat acute pain model.

For research use only. We do not sell to patients.

ALX-1393 Chemical Structure

ALX-1393 Chemical Structure

CAS No. : 949164-09-4

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Description

ALX-1393, a selective GlyT2 inhibitor, has an antinociceptive effect on thermal, mechanical, and chemical stimulations in a rat acute pain model[1].

IC50 & Target

GlyT2[1]

In Vivo

ALX1393 (i.c.v.; 25, 50, and 100 μg) in normal rats suppresses the late-phase response in the formalin test but does not affect motor performance. ALX1393 inhibits mechanical and cold hyperalgesia in a dose-dependent manner[2].

Molecular Weight

395.42

Formula

C₂₃H₂₂FNO₄

CAS No.

949164-09-4

SMILES

N[[email protected]@H](COC(C1=CC=CC(F)=C1)C2=CC=CC=C2OCC3=CC=CC=C3)C(O)=O

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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ALX-1393
Cat. No.:
HY-111029
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