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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
94 Results for "
acetaminophen
" in MedChemExpress (MCE) Product Catalog:
Products (94)
94 Results for "acetaminophen" in MCE Product Catalog:
Cat. No.: HY-G0004
CAS No.: 37519-14-5
Synonyms: 3-Hydroxyacetaminophen
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Acetaminophen metabolite 3-hydroxy-acetaminophen (3-Hydroxyacetaminophen) is a non-toxic metabolite and antioxidant of acetaminophen (HY-66005) with free radical scavenging activity. Acetaminophen metabolite 3-hydroxy-acetaminophen can reduce oxidative damage by exerting electron donation ability and antioxidant activity through phenolic hydroxyl groups. 3-hydroxy-acetaminophen can be used to study the toxicity mechanism and drug metabolism of acetaminophen .
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FH1 (NSC 12407) is a NQO2 inhibitor with hepatoprotective effects. FH1 enhances hepatocyte function and promotes differentiation of induced pluripotent stem (iPS)-derived hepatocytes to a more mature phenotype and maturation of well-differentiated hepatocyte-like cell (iHeps) cultures. FH1 protects against Acetaminophen (HY-66005)-induced hepatotoxicity in both embryos and adult zebrafish .
Cat. No.: HY-P5362
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Cat. No.: HY-66005S1
CAS No.: 60902-28-5
Synonyms: Paracetamol-d3; 4-Acetamidophenol-d3; 4'-Hydroxyacetanilide-d3
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4-Acetamidophenyl acetate is an impurity of Acetaminophen (HY-66005). 4-Acetamidophenyl acetate acts as an intermediate in the synthesis of Acetaminophen. Acetaminophen is a selective COX-2 inhibitor (IC50=25.8 μM), and is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor .
Cat. No.: HY-W019704
CAS No.: 1115-47-5
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Propacetamol is an orally active prodrug of Acetaminophen (HY-66005), which exerts antipyretic and analgesic effects after metabolism. Propacetamol reduces Aspirin (ASA) (HY-14654)-induced elevation of malondialdehyde (MDA) in gastric mucosa and plasma, regulates the levels of gastric mucosal glutathione (GSH and GSSG) to maintain cellular antioxidant defense, and increases gastric mucosal uric acid (UA) levels. Propacetamol exerts a dose-dependent protective effect against ASA-induced gastric mucosal damage in rats. Propacetamol can be used for the study of gastric mucosal injury by interfering with oxidative stress .
Cat. No.: HY-66005S2
CAS No.: 1219798-53-4
Synonyms: Paracetamol-d7; 4-Acetamidophenol-d7; 4'-Hydroxyacetanilide-d7
Cat. No.: HY-W010800R
CAS No.: 1510-21-0
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Cholesteryl hemisuccinate (Standard) is the analytical standard of Cholesteryl hemisuccinate. This product is intended for research and analytical applications. Cholesteryl hemisuccinate is a with hepatoprotective an anticancer activity. Cholesteryl hemisuccinate inhibits Acetaminophen (AAP, HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis. Cholesteryl hemisuccinate inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Thus, Cholesteryl hemisuccinate inhibits tumor growth[1][2].
Cat. No.: HY-66005S4
CAS No.: 360769-21-7
Synonyms: Paracetamol-13C2,15N; 4-Acetamidophenol-13C2,15N; 4'-Hydroxyacetanilide-13C2,15N
Cat. No.: HY-139093
CAS No.: 53446-10-9
Synonyms: APAP-Cys
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Paracetamol-cysteine (APAP-Cys) is a cysteine adduct of Acetaminophen (HY-66005). It forms when Acetaminophen is oxidized to the reactive metabolite N-acetyl-p-benzoquinone imine (NAPQI) .
Cat. No.: HY-W012790S
CAS No.: 1219798-97-6
Cat. No.: HY-138128
CAS No.: 52372-86-8
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Acetaminophen mercapturate is a metabolite of Acetaminophen. Acetaminophen is a selective COX-2 inhibitor .
Cat. No.: HY-N7697C
CAS No.: 127171-88-4
Cat. No.: HY-66006AS
CAS No.: 1188263-45-7
Cat. No.: HY-66005S3
CAS No.: 2132405-57-1
Synonyms: Paracetamol-13C6; 4-Acetamidophenol-13C6; 4'-Hydroxyacetanilide-13C6
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4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol). Acetaminophen is a potent cyclooxygenase-2 (COX-2) and hepatic N-acetyltransferase 2 (NAT2) inhibitor, and used antipyretic and analgesic agent .
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4-Acetamidophenyl acetate (Standard) is the analytical standard of 4-Acetamidophenyl acetate (HY-66004). This product is intended for research and analytical applications. 4-Acetamidophenyl acetate is an impurity of Acetaminophen (HY-66005). 4-Acetamidophenyl acetate acts as an intermediate in the synthesis of Acetaminophen. Acetaminophen is a selective COX-2 inhibitor (IC50=25.8 μM), and is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor .
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2,4'-Dihydroxybenzophenone ((Z)-SU4312) exhibited estrogenic activities. 2,4'-Dihydroxybenzophenone has oral bioactivity that can effectively protect C57BL/6J mice from Acetaminophen (HY-66005, APAP)-induced hepatotoxicity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
