2424 Results for "

decrease

" in MedChemExpress (MCE) Product Catalog:
Products (2424)

2424 Results for "decrease" in MCE Product Catalog:

Cat. No.: HY-19690
CAS No.: 476333-91-2
Synonyms: KUC-7483 hydrochloride
Target:  

Adrenergic Receptor

Research Areas:  

Metabolic Disease Endocrinology

Ritobegron, a prodrug of the active compound, KUC-7322, is a selective β3 -adrenoceptor agonist. Ritobegron decreases intravesical pressure with minimal effects on the cardiovascular system.
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Cat. No.: HY-N11948
CAS No.: 51771-52-9
Simmondsin, derived from the jojoba plant (Simmondsia chinensis), has been shown to decrease food intake and body weight in rats without any noticeable adverse effects.
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Cat. No.: HY-N12158
CAS No.: 71627-22-0
Pipermethystine is an alkaloid that can be isolated from the Kava plant. Pipermethystine decreases HepG2 cell cellular ATP levels, mitochondrial membrane potential, and induces apoptosis .
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Cat. No.: HY-N7709
CAS No.: 85022-68-0
Cinchonain IIb is a proanthocyanidin. Cinchonain IIb has the effect of rational utilization of decreased cardiac function. Cinchonain IIb is isolated from natural hawthorn (Crataegus spp. ) .
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Cat. No.: HY-P0251A
CAS No.: 2952825-79-3
Target:  

Neurotensin Receptor

Research Areas:  

Neurological Disease

Neurotensin (8-13) is an active fragment of Neurotensin. Neurotensin(8-13) TFA results in a decrease in cell-surface NT1 receptors (NTR1) density.
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Cat. No.: HY-124412S
Paynantheine-d3 is a deuterium labeled Paynantheine. Paynantheine is an alkaloid that can be isolated from Mitragyna speciosa. Paynantheine can decrease alcohol intake in mice .
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Cat. No.: HY-135381
CAS No.: 887196-30-7
Target:  

Drug Metabolite

Research Areas:  

Cardiovascular Disease

3-Oxo Atorvastatin is an impurity of 3-Oxo Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids .
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Cat. No.: HY-136568
CAS No.: 2582755-72-2
Purity:  98.31%
Target:  

STAT

Research Areas:  

Others

Stafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM) decreases pSTAT5a expression significantly, and has no obvious inhibition on pSTAT5b .
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Cat. No.: HY-136961
CAS No.: 35020-81-6
Synonyms: NK266 orotate
Target:  

Fungal

Research Areas:  

Infection

NK 1971 (NK266 orotate) is a derivative of NK266 and shows potential antifungal activity. NK 1971 may result in decreased motor skills and seizures in animals .
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Cat. No.: HY-144752
Synonyms: Cyclic spermine
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

cSPM (Cyclic spermine) is a Aβ42 inhibitor. cSPM could suppress the aggregation of three different peptides, Aβ42, amylin and insulin, and decreases cytotoxicity .
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Cat. No.: HY-160433
CAS No.: 364039-56-5
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

TNF-α-IN-12 is a TNF-α inhibitor with IC50 of 0.1 μM. TNF-α-IN-12 can decrease the TNF-α blood levels .
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Cat. No.: HY-163848
CAS No.: 3053522-48-5
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Anti-inflammatory agent 90 (compound (R)-7) demonstrates decreasing of 32 % and 40 % for nitrite and IL-6, respectively in LPS-challenged RAW cells .
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Cat. No.: HY-168538
Target:  

Paraptosis

Research Areas:  

Infection

Antitrypanosomal agent 21 (Compound C-1) is a trypanosoma brucei inhibitor. Antitrypanosomal agent 21 decreases the level of D6XM23 in parasite lysates .
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Cat. No.: HY-177852
CAS No.: 873556-29-7
Target:  

Bacterial

Research Areas:  

Infection

Anthranilyl-AMSN is a potent PqsA inhibitor, with a Kiapp of 170 nM. Anthranilyl-AMSN decreases HHQ and PQS production. Anthranilyl-AMSN can be used in the research of Pseudomonas aeruginosa infections .
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Cat. No.: HY-N3960
CAS No.: 66056-18-6
Glycyrin is a PPAR-γ ligand of licorice. Glycyrin can decrease the blood glucose levels of genetically diabetic mice. Glycyrin also shows antibacterial activity .
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Cat. No.: HY-N9516
CAS No.: 517-37-3
Synonyms: TDHC
Category:  

Animal Steroids

Target:  

Endogenous Metabolite

Taurodehydrocholic acid is a biliary cholesterol secretion activator. Taurodehydrocholic acid significantly increases the expression of Abcg5 and decreases the expression of abc8. Taurodehydrocholic acid can be used in the study of cholesterol metabolism .
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Cat. No.: HY-N9516A
CAS No.: 57011-24-2
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Taurodehydrocholic acid sodium is a biliary cholesterol secretion activator. Taurodehydrocholic acid sodium significantly increases the expression of Abcg5 and decreases the expression of abc8. Taurodehydrocholic acid sodium can be used in the study of cholesterol metabolism .
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Cat. No.: HY-W168754
CAS No.: 16296-42-7
Target:  

MHC

Research Areas:  

Others

DB28 is a novel MR1 ligand. DB28 decreases cell surface expression of MR1 and competitively inhibits activation of MAIT cells by agonist ligands .
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Cat. No.: HY-Z7628
CAS No.: 433289-83-9
Target:  

Drug Intermediate

Research Areas:  

Others

Atorvastatin impurity 2 calcium is an impurity of Atorvastatin (HY-B0589). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids.
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Cat. No.: HY-100987
CAS No.: 14919-37-0
Research Areas:  

Others

Lauroylcarnitine chloride enhances the absorption of salmon calcitonin in rats. Also in determining in situ bioavailability, increased availability of Lucifer yellow and decreased expression of claudin-4 protein in the colon .
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