2424 Results for "

decrease

" in MedChemExpress (MCE) Product Catalog:
Products (2424)

2424 Results for "decrease" in MCE Product Catalog:

Cat. No.: HY-103232
CAS No.: 258282-23-4
Target:  

mGluR

Research Areas:  

Neurological Disease

IEM-1925 bromide is an orally active glutamate receptor antagonist, increases the latent period and decreases the duration of status epilepticus in rats in a lithium-pilocarpine model of epilepsy .
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Cat. No.: HY-107906
CAS No.: 12126-59-9
Target:  

Estrogen Receptor/ERR

Research Areas:  

Endocrinology

Conjugated estrogen sodium is a medication composed of a blend of estrogen hormones, utilized in the treatment of moderate to severe hot flashes, vaginal changes, and various other symptoms associated with menopause or decreased estrogen levels.
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Cat. No.: HY-108560A
CAS No.: 54276-24-3
Research Areas:  

Others

15(S)-Fluprostenol is the isomer of (+)-Fluprostenol (HY-108560). (+)-Fluprostenol is a potent agonist of PTGER2. (+)-Fluprostenol decreases the expression of Oviductal glycoprotein 1 (OVGP1) .
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Cat. No.: HY-114909
CAS No.: 331839-29-3
Target:  

Parasite

Research Areas:  

Infection

TachypleginA can inhibit the motility of T. gondii by binding directly and covalently to C58 of TgMLC1,thereby causing a decrease in the activity of the parasite's myosin motor .
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Cat. No.: HY-115429
CAS No.: 115940-48-2
Synonyms: (6R)-Leucovorin calcium; (6R)-Folinic acid calcium
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

Calcium dextrofolinate is a stereoisomer of Calcium folinate. Calcium folinate (Folinic acid calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity .
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Cat. No.: HY-118470
CAS No.: 5696-15-1
Purity:  99.87%
Synonyms: Butoxamin hydrochloride
Target:  

Adrenergic Receptor

Research Areas:  

Endocrinology

Butaxamine (Butoxamin) hydrochloride is a specific β2-adrenergic receptor blocker. Butaxamine hydrochloride inhibits the decreases in urine volume in ethanol-anesthetized, water-diuretic rats .
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Cat. No.: HY-124501
CAS No.: 1814-64-8
Purity:  99.24%
Synonyms: p-NH2-PE-TFMPP
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

LY 165163 is a potent 5-HT presynaptic receptor agonist. LY 165163 significantly decreases 5-HTP accumulation and increases DOPA accumulation in the cortex and striatum .
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Cat. No.: HY-124597
CAS No.: 1628343-77-0
Purity:  95.00%
Target:  

Ceramidase

Research Areas:  

Inflammation/Immunology

ARN726 is a potent NAAA (N-acylethanolamine acid amidase) inhibitor with an IC50 of 0.073 µM. ARN726 decreases alcohol self-administration in a dose-dependent manner .
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Cat. No.: HY-135380
CAS No.: 125971-95-1
Purity:  99.94%
Target:  

Drug Intermediate

Research Areas:  

Cardiovascular Disease

Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids .
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Cat. No.: HY-147784
CAS No.: 2041789-14-2
Target:  

Btk

Research Areas:  

Cancer

HZ-A-005 is a potent, selective, and covalent Bruton’s tyrosine kinase (BTK) inhibitor. HZ-A-005 markedly decreases tumor growth in xenograft mouse models .
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Cat. No.: HY-153740
CAS No.: 2498597-94-5
Purity:  99.37%
Synonyms: ARRY-558
Target:  

SHP2

Research Areas:  

Cancer

PF-07284892 (ARRY-558) is a potent and orally active SHP2 inhibitor with an IC50 value of 21 nM. PF-07284892 decreases the expression of pERK .
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Cat. No.: HY-168363
CAS No.: 58765-21-2
Synonyms: WE-973
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Ciclotizolam (WE-973) is a thienotriazolodiazepine with anticonvulsant and anti-aggressive activities. Ciclotizolam binds to benzodiazepine receptors in the central nervous system. Ciclotizolam decreases total sleep time in cats .
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Cat. No.: HY-21196A
CAS No.: 3871-99-6
Target:  

Phosphatase

Research Areas:  

Metabolic Disease

Potassium perfluorohexanesulfonate is an orally active surfactant found in sera of the general population. Potassium perfluorohexanesulfonate induces adaptive hepatocellular hypertrophy, decreases serum cholesterol and increases alkaline phosphatase in male mice .
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Cat. No.: HY-A0171A
CAS No.: 10085-81-1
Synonyms: Ba-30803
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

Benzoctamine hydrochloride (Ba-30803) is a psychoactive agent with anti-anxiety effect. Benzoctamine hydrochloride blocks the central postsynaptic serotonin receptors and decreases 5-HT turnover in the brain .
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Cat. No.: HY-P11482
Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Nesfatin-1 (24-53), mouse/rat is a peptide. Nesfatin-1 (24-53), mouse/rat significantly decreases food intake, inhibits gastroduodenal motility .
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Cat. No.: HY-P2052
CAS No.: 140716-14-9
Research Areas:  

Others

AWL 60 is a compound with SP antagonist and weak opioid agonist properties, which can antagonize SP-agonists in vitro and attenuate the decrease in blood pressure caused by SP-agonists in vivo.
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Cat. No.: HY-P3973
CAS No.: 929555-19-1
Target:  

Bradykinin Receptor

Research Areas:  

Others

Thrombostatin cont-1 is an analogue of thrombostatin, which is a a bradykinin metabolite. Thrombostatin could decrease platelet activation in the canine carotid artery model of balloon angioplasty (BA) injury .
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Cat. No.: HY-W017423
CAS No.: 6485-40-1
(-)-Carvone is an insect neurotoxin and a irreversible acetylcholinesterase (AChE) inhibitor. (-)-Carvone can be used as a bird repellent, inhibits larval growth, decreases pupatation rate, and increases mortality of larvae .
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Cat. No.: HY-107754
CAS No.: 7647-17-8
Purity:  99.93%
Cesium chloride is a blocker of potassium channel. Cesium chloride prevents the decrease of Na + transport produced by Alloxan . Cesium chloride has induced cardiac arrhythmias, including torsade de pointes in animal models .
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Cat. No.: HY-108560R
CAS No.: 54276-17-4
Research Areas:  

Others

(+)-Fluprostenol (Standard) is the analytical standard of (+)-Fluprostenol. This product is intended for research and analytical applications. (+)-Fluprostenol is a potent agonist of PTGER2. (+)-Fluprostenol decreases the expression of Oviductal glycoprotein 1 (OVGP1) .
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