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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
108 Results for "
Antispasmodic
" in MedChemExpress (MCE) Product Catalog:
Products (108)
108 Results for "Antispasmodic" in MCE Product Catalog:
Cat. No.: HY-B0267B
CAS No.: 1207344-05-5
Synonyms: Aroxybutynin hydrochloride
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(R)-Oxybutynin hydrochloride (Aroxybutynin hydrochloride), an enantiomer of Oxybutynin hydrochloride, is an orally active muscarinic receptor antagonist. (R)-Oxybutynin hydrochloride exhibits antispasmodic and anticholinergic activities, and competitively antagonizes carbachol-induced contractions. (R)-Oxybutynin hydrochloride can be used in the research of urinary incontinence caused by neurogenic bladder dysfunction .
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Alimemazine is a phenothiazine derivative that is generally used as an antipruritic agent and also a hemagglutinin (HA)-receptor antagonist.Alimemazine (Trimeprazine) is also acts as a partial agonist against the histamine H1 receptor (H1R) and other GPCRs. Alimemazine displays antiserotonin, antispasmodic, and antiemetic properties .
Cat. No.: HY-128891
CAS No.: 64840-90-0
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Eperisone ((±)-Eperisone) is an antispasmodic agent and centrally acting muscle relaxant useful in the study of diseases characterized by muscle stiffness and pain. Eperisone acts by relaxing skeletal and vascular smooth muscle, resulting in vasodilation, decreased muscle tone, improved circulation, and inhibition of pain reflexes. Eperisone is also a potent P2X7 receptor antagonist .
Cat. No.: HY-13557R
CAS No.: 104987-12-4
Synonyms: Immunomycin (Standard); FR-900520 (Standard); FK520 (Standard)
Category:
Microorganisms Macrolide Antibiotics Antifungal Anti-inflammation/Immunoregulatory Antibiotics Disease Research
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1-Naphthylacetamide is an orally active nonsteroidal anti-inflammatory agent (NAIA) and also an indole-type auxin plant growth regulator. 1-Naphthylacetamide inhibits inflammatory response-related pathways and modulates plant hormone signaling, exhibiting anti-inflammatory, local anesthetic, antispasmodic, analgesic, and diuretic activities. 1-Naphthylacetamide promotes plant cell expansion, differentiation, and fruit enlargement. Additionally, 1-Naphthylacetamide induces central nervous system (CNS) depression in mice, characterized by reduced spontaneous activity, decreased irritability, decreased muscle tone, and attenuated ear-cuff reflex, ipsilateral flexor reflex, and corneal reflex [1][2].
Cat. No.: HY-B0549
CAS No.: 15301-69-6
Synonyms: Rec-7-0040 free base; DW61 free base
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Flavoxate (Rec-7-0040 free base; DW61 free base) is an orally active L-type Ca 2+ channel inhibitor and antispasmodic. Flavoxate inhibits cyclic adenosine monophosphate production by blocking voltage-dependent inward Ba 2+ currents, regulating the brainstem micturition center, and stimulating G protein-coupled receptors. Consequently, Flavoxate induces relaxation of bladder smooth muscle and inhibits isovolumetric rhythmic contractions. Flavoxate effectively increases bladder capacity and alleviates symptoms of urgent urination frequency and pollakiuria caused by overactive bladder. Flavoxate can be used in research on overactive bladder and related voiding dysfunctions .
Cat. No.: HY-100679A
CAS No.: 207572-66-5
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Pirlindole mesylate is an orally active, selective and reversible MAO-A inhibitor with an IC50 value of 250 nM. Pirlindole mesylate inhibits genomic replication of Enterovirus species B and D, and exhibits moderate activity against enterovirus species A. Pirlindole mesylate inhibits MAO-A-mediated monoamine metabolism, promotes adult hippocampal neurogenesis, rescues stress-induced dendritic atrophy of hippocampal granule neurons, reverses behavioral effects associated with chronic mild stress, and also possesses anticonvulsant, analgesic, local anesthetic, hypotensive, antiplatelet aggregation and antispasmodic activities. Pirlindole mesylate shows no detectable mutagenic, clastogenic or carcinogenic properties. Pirlindole mesylate can be used in research related to depression and enterovirus infections .
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Piperylone can be used as an antispasmodic.
Cat. No.: HY-133153S
Purity: 99.46%
Cat. No.: HY-136634
CAS No.: 72293-40-4
BTM-1042 is a newly synthesized compound with antispasmodic effects. It can inhibit the twitch reaction of the guinea pig ileum under electrical stimulation and is not affected by naloxone. It has similar effects to atropine and can block muscarinic receptors, but has less effect on other types of receptors. BTM-1042 also has an inhibitory effect on the ileal reaction caused by nicotine and 5-hydroxytryptamine. BTM-1042 showed a dose-dependent inhibitory effect on the spontaneous movement of the rabbit stomach. In general, BTM-1042 is a agent with a strong antispasmodic effect.
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Iridoids Terpenoids Scrophulariaceae Extract Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey
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Cat. No.: HY-12769S1
Purity: ≥99.0%
Synonyms: Mebeverine metabolite Mebeverine acid-d5 hydrochloride
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Dicyclomine (Dicycloverine) is a potent and orally active muscarinic cholinergic receptors antagonist. Dicyclomine (Dicycloverine) shows high affinity for muscarinic M1 receptor subtype (Ki=5.1 nM) and M2 receptor subtype (Ki=54.6 nM) in brush-border membrane and basal plasma membranes, respectively . Dicyclomine is an antispasmodic agent and relieves smooth muscle spasm of the gastrointestinal tract in vivo .
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Cat. No.: HY-105738
CAS No.: 55837-14-4
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Butaverine is an antispasmodic compound .
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Pyrophendane is an antispasmodic agent .
Cat. No.: HY-W201842
CAS No.: 502-59-0
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Octamylamine is an anticholinergic and antispasmodic agent .
Cat. No.: HY-W201842B
CAS No.: 5964-56-7
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Octamylamine hydrochloride is an anticholinergic and antispasmodic agent .
Cat. No.: HY-W201842A
CAS No.: 96296-56-9
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Octamylamine sulfamate is an anticholinergic and antispasmodic agent .
Cat. No.: HY-N4113R
CAS No.: 94805-82-0
Category:
Coumarins Phenols Polyphenols Leguminosae Extract Phenylpropanoids Plants Glycyrrhiza uralensis Fisch.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
