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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
69 Results for "
CARD
" in MedChemExpress (MCE) Product Catalog:
Products (69)
69 Results for "CARD" in MCE Product Catalog:
Cat. No.: HY-P703369
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CARD11; Carma 1; Caspase Recruitment Domain Family Member 11; Caspase Recruitment Domain Family, Member 11; CARMA1; CARD-Maguk Protein 1; Caspase Recruitment Domain-Containing Protein 11; IMD11A; BIMP3; IMD11; Bcl10-Interacting Maguk Protein 3; BENTA; CAR
Species:
Human
Source:
E. coli
Cat. No.: HY-P703082
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: MAVS; Mitochondrial Antiviral-Signaling Protein; Mitochondrial Antiviral Signaling Protein; CARD Adapter Inducing Interferon Beta; CARDif; Virus-Induced Signaling Adaptor; IPS-1; Virus-Induced-Signaling Adapter; VISA; CARD Adaptor Inducing IFN-Beta; KIAA1
Species:
Human
Source:
E. coli
Cat. No.: HY-P80582A
Synonyms: Caspase recruitment domain-containing protein 9; hCARD9
Cat. No.: HY-103479R
CAS No.: 1452473-54-9
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
GOAT-IN-1 (Standard) is the analytical standard of GOAT-IN-1 (HY-103479). This product is intended for research and analytical applications. GOAT-IN-1 is an inhibitor of ghrelin O-acyltransferase (GOAT), which could be useful for the prophylaxis or treatment of obesity, diabetes, hyperlipidemia, metabolic, non-alcoholic fatty liver, steatohepatitis, sarcopenia, appetite control, alcohol/narcotic dependence, Alzheimer’s disease, Parkinson’s disease, cerebrovascular dementia, cerebral apoplexy, cerebral infarction, cardic disease, some kind of tumors.
Cat. No.: HY-P706241
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RIPK2; Receptor-Interacting Protein (RIP)-Like Interacting Caspase-Like Apoptosis Regulatory Protein (CLARP) Kinase; Receptor Interacting Serine/Threonine Kinase 2; CARD-Containing Interleukin-1 Beta-Converting Enzyme (ICE)-Associated Kinase; CARDIAK; CARD-Containing Interleukin-1 Beta-Converting Enzyme-Associated Kinase; RIP2; Receptor-Interacting Serine-Threonine Kinase 2 Isoform B; RICK; Receptor-Interacting Serine-Threonine Kinase 2 Isoform 2; Receptor-Interacting Serine/Threonine-Protein Kinase 2; Receptor-Interacting Serine-Threonine Kinase 2; Receptor-Interacting Protein 2; RIP-Like-Interacting CLARP Kinase; Tyrosine-Protein Kinase RIPK2; Growth-Inhibiting Gene 30; CARD3; CARD-Carrying Kinase; CARD-Containing IL-1 Beta ICE-Kinase; GIG30; RIP-2; CCK
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P81443
Synonyms: BCL10; CIPER; CLAP; B-cell lymphoma/leukemia 10; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog
Cat. No.: HY-P81443A
Synonyms: BCL10; CIPER; CLAP; B-cell lymphoma/leukemia 10; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog
Cat. No.: HY-183739
CAS No.: 441022-67-9
Target:
Research Areas:
CQ31 is a PEPD and XPNPEP1 inhibitor, with an IC50 of 0.67 μM against PEPD and an IC50 of 122 μM against XPNPEP1. CQ31 inhibits the M24B aminopeptidase activity of PEPD and XPNPEP1. CQ31 induces the accumulation of Xaa-Pro-containing peptides, mildly inhibits DPP8/9, and triggers CASP1-dependent pyroptosis via activation of the CARD8 inflammasome and caspase-1. CQ31 can be used in research related to cancers such as acute myeloid leukemia .
Cat. No.: HY-P703357
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NOD2; Caspase Recruitment Domain Family, Member 15; Prev. CARD15; Inflammatory Bowel Disease Protein 1; Prev. IBD1; NOD-Like Receptor C2; Nucleotide-Binding Oligomerization Domain-Containing Protein 2; Nucleotide-Binding Oligomerization Domain Containing 2; Caspase Recruitment Domain-Containing Protein 15; Nucleotide-Binding Oligomerization Domain 2; PSORAS1; Caspase Recruitment Domain Protein 15; CLR16.3; NOD2 Protein; NLRC2; BLAUS; BLAU; NOD2B; CD; ACUG; Nucleotide-Binding Oligomerization Domain, Leucine Rich Repeat And CARD Domain Containing 2; YAOS; Nucleotide Binding Oligomerization Domain Containing 2; NLR Family, CARD Domain Containing 2
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P89570
Synonyms: CARD7, DEFCAP, KIAA0926, NAC, NALP1, NLRP1, Caspase recruitment domain-containing protein 7, Death effector filament-forming ced-4-like apoptosis protein, Nucleotide-binding domain and caspase recruitment domain
Cat. No.: HY-P86956
Synonyms: CARD adapter inducing interferon beta antibody; CARD adaptor inducing IFN beta antibody; CARDif antibody; DKFZp666M015 antibody; FLJ27482 antibody; FLJ41962 antibody; IFN B promoter stimulator 1 antibody; Interferon beta promoter stimulator protein 1 antibody; Ips 1 antibody; IPS-1 antibody; CARD adapter inducing interferon beta antibody; CARD adaptor inducing IFN beta antibody; CARDif antibody; DKFZp666M015 antibody; FLJ27482 antibody; FLJ41962 antibody; IFN B promoter stimulator 1 antibody; Interferon beta promoter stimulator protein 1 antibody; Ips 1 antibody; IPS-1 antibody; Ips1 antibody; KIAA1271 antibody; MAVS antibody; MAVS_HUMAN antibody; Mitochondrial anti viral signaling protein antibody; Mitochondrial Antiviral Signaling antibody; Mitochondrial antiviral signaling protein antibody; Mitochondrial antiviral-signaling protein antibody; Putative NF kappa B activating protein 031N antibody; Putative NF-kappa-B-activating protein 031N antibody; Virus induced signaling adapter antibody; virus induced signaling adaptor antibody; Virus-induced-signaling adapter antibody; VISA antibody;
Cat. No.: HY-W017087
CAS No.: 135-77-3
Research Areas:
1,2,4-Trimethoxybenzene is an orally active NLRP3 selective inhibitor. 1,2,4-Trimethoxybenzene can markedly suppress Nigericin (HY-127019) or ATP (HY-B2176)-induced NLRP3 inflammasome activation, thus decreasing caspase-1 activation and IL-1β secretion. 1,2,4-Trimethoxybenzene specifically inhibits the activation of NLRP3 inflammasome without affecting absent in melanoma 2 (AIM2) inflammasome activation. 1,2,4-Trimethoxybenzene inhibits oligomerization of the apoptosis-associated speck-like protein containing a CARD (ASC) and protein-protein interaction between NLRP3 and ASC, thus blocking NLRP3 inflammasome assembly. 1,2,4-Trimethoxybenzene can be used for the study of experimental autoimmune encephalomyelitis (EAE), multiple sclerosis, and type 2 diabetes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
