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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
113 Results for "
ER dilation
" in MedChemExpress (MCE) Product Catalog:
Products (113)
113 Results for "ER dilation" in MCE Product Catalog:
Cat. No.: HY-P10554
CAS No.: 171675-09-5
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Myhc-α(334–352) is a sequence fragment of amino acid residues 334 to 352 of cardiac myosin heavy chain α. Myhc-α(334–352) is an immunodominant epitope that can induce autoimmune reactions in A/J mice, leading to the occurrence of myocarditis. Myhc-α(334–352) can be used to study the autoimmune pathways of myocarditis and dilated cardiomyopathy .
Cat. No.: HY-19664
CAS No.: 99522-79-9
Synonyms: OPC-13340
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Pranidipine (OPC-13340) is an orally active L-type voltage-dependent calcium channel (L-VDCC) blocker with a Ki value of 0.16 nM. Pranidipine inhibits calcium-induced contraction, suppresses slow-response action potentials, shortens action potential duration, reduces systolic and diastolic blood pressure, and exerts vasodilatory effects. Pranidipine enhances its vasodilatory effect by blocking NO decomposition. Pranidipine can be used in research related to essential hypertension, angina pectoris, myocardial infarction, and dilated cardiomyopathy .
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Cat. No.: HY-101952S1
CAS No.: 1356347-42-6
Synonyms: PGE2-d9; Dinoprostone-d9
Research Areas:
Prostaglandin E2-d9 is the deuterium labeled Prostaglandin E2. Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation .
Synonyms: PF-07265803; ARRY-797; ARRY-371797
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Emprumapimod (PF-07265803) is a potent, orally active and selective inhibitor of p38α MAPK directly inhibits LPS-induced IL-6 production from RPMI-8226 cell (IC50=100 pM). Emprumapimod can be used for the research of dilated cardiomyopathy and acute inflammatory pain .
Cat. No.: HY-P10887
CAS No.: 2988012-71-9
Synonyms: AV-001
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Tie ANGPTL SARS-CoV Aquaporin TNF Receptor PAI-1 CXCR P-selectin
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Cardiovascular Disease Neurological Disease Inflammation/Immunology
p38α inhibitor 1 (Arry-797) is a p38α inhibitor. p38α inhibitor 1 is applicable to research related to diseases including Alzheimer's disease and inflammatory dilated cardiomyopathy .
Cat. No.: HY-B0642R
CAS No.: 16051-77-7
Synonyms: Isosorbide-5-mononitrate (Standard)
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Cat. No.: HY-B0321S
CAS No.: 2673270-13-6
Synonyms: Ro 1-7683-d3
Cat. No.: HY-P5226
CAS No.: 936544-53-5
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Palmitoyl tripeptide-8 is an immunomodulatory peptide and neurotransmitter inhibitory peptide. Palmitoyl tripeptide-8 inhibits the activation of the NF-κB pathway and the production of pro-inflammatory cytokines (IL-8, IL-6, and TNF-α). Palmitoyl tripeptide-8 activates the cutaneous opioid system and reduces CGRP release. Palmitoyl tripeptide-8 decreases the number of dilated capillaries, the size of dilated vessels, and the degree of edema in skin explants treated with Substance P (HY-P0201). Palmitoyl tripeptide-8 is used as an active ingredient in cosmetics for sensitive skin. Palmitoyl tripeptide-8 is utilized in research related to sensitive skin .
Cat. No.: HY-148400
CAS No.: 913541-96-5
Synonyms: TXC hydrochloride
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Cetyl tranexamate (TXC) hydrochloride is an ester derivative of Tranexamic acid (HY-B0149). Cetyl tranexamate hydrochloride is an inhibitor of fibrinogen activation and can reduce the production of fibrinogen in keratinocytes induced by ultraviolet rays or damage, indirectly inhibiting the melanin production pathway. Cetyl tranexamate hydrochloride also targets melanin (dark spots) and hemoglobin (red spots), reducing vascular dilation and pigmentation by inhibiting inflammatory mediators (such as prostaglandins, platelet activating factors). Cetyl tranexamate hydrochloride can be used as a cosmetic ingredient and is suitable for epidermal pigment disorders such as photoaging, post-inflammatory hyperpigmentation (PIH), and melasma .
Cat. No.: HY-U00172
CAS No.: 83656-38-6
Synonyms: C80-1324
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Ipramidil (C80-1324) is a vasodilator with significant active dilation of coronary circulation in isolated hearts. Ipramidil can cause an increase in NO release and stimulate guanylate cyclase activity.
Cat. No.: HY-150092
CAS No.: 123931-39-5
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Cat. No.: HY-Z7082
CAS No.: 612548-45-5
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Perindopril L-arginine is an orally active and selective angiotensin-converting enzyme (ACE) inhibitor. Perindopril L-arginine reduces the production of angiotensin II by inhibiting ACE, thereby dilating blood vessels, lowering blood pressure, and also exerting activities such as vasculoprotection and antithrombosis. Perindopril L-arginine is promising for research of cardiovascular diseases .
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Research Areas:
Infection Neurological Disease Inflammation/Immunology Endocrinology
Hexoprenaline is an orally active and selective β-adrenergic receptor agonist. Hexoprenaline can dilate the bronchi. Hexoprenaline can activate adenylate cyclase and increases 14C-Aminopyrine uptake. Hexoprenaline exhibits anti-infection and anti-inflammmation effect. Hexoprenaline can increase placental weight and blood flow. Hexoprenaline can be used for the researches of inflammation, immunology, infection, endocrinology and neurological disease, such as asthma, chronic bronchitis, sepsis and intoxication of organophosphorus compounds .
Cat. No.: HY-B0347S1
CAS No.: 1261432-01-2
Cat. No.: HY-N12777
CAS No.: 29066-43-1
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Hydroxyamphetamine (4-Hydroxyamphetamine) is a sympathomimetic agent, stimulates the sympathetic nervous system. Hydroxyamphetamine can be used in eye drops to dilate the pupil .
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Hydroxyamphetamine (4-Hydroxyamphetamine) hydrobromide is a sympathomimetic agent, stimulates the sympathetic nervous system. Hydroxyamphetamine hydrobromide can be used in eye drops to dilate the pupil .
Cat. No.: HY-119544
CAS No.: 148504-51-2
Synonyms: UP-2696
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Ripisartan (UP-2696) is an angiotensin II receptor antagonist. Ripisartan is orally available. Ripisartan binds to angiotensin II receptors, dilates blood vessels, and lowers blood pressure .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
