119 Results for "

Intraocular Pressure

" in MedChemExpress (MCE) Product Catalog:
Products (119)

119 Results for "Intraocular Pressure" in MCE Product Catalog:

Cat. No.: HY-101303
CAS No.: 190277-13-5
Target:  

Melatonin Receptor

Research Areas:  

Others

5-MCA-NAT is a melatonin agonist that may target the melatoninMT3 receptor. 5-MCA-NAT can contract the colonic band in a concentration-dependent manner and reduce intraocular pressure (IOP) in glaucomatous monkey eyes, inhibiting the increase in IOP .
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Cat. No.: HY-185048
PCB-OAA is a biocompatible multivinyl polycarboxybetaine macromonomer and that exhibits anti-fouling activity. PCB-OAA can form a hydrogel in vitreous cavity and shows an appealing ability to prevent significantly inflammatory response, fibrosis and complications such as raised intraocular pressure, and cataract formation. PCB-OAA can be used for the research of vitreous substitution .
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Cat. No.: HY-121398
CAS No.: 52365-63-6
Dipivefrin is an α/β-adrenoceptor agonist and a prodrug of epinephrine. Dipivefrin regulates intraocular pressure by agonizing α/β-adrenoceptors and modulating the aqueous humor outflow pathway. Dipivefrin acts on neuroblastoma cells and downregulates glutamate-induced intracellular calcium levels. Dipivefrin is used in research related to α/β-adrenoceptor-mediated diseases, such as glaucoma .
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Cat. No.: HY-121902
CAS No.: 7433-10-5
Target:  

Adrenergic Receptor

Research Areas:  

Others

Butidrine is a compound with intraocular pressure-lowering activity that is less effective than some other beta-adrenergic receptor blockers in reducing intraocular pressure in rabbit eyes.
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Cat. No.: HY-118656
CAS No.: 31508-71-1
Target:  

Cannabinoid Receptor

Research Areas:  

Neurological Disease

Cannabicitran is a cannabinoid. Cannabicitran can decrease intraocular pressure in rabbits .
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Cat. No.: HY-153483A
Synonyms: SYL040012 sodium
Research Areas:  

Others

Bamosiran sodium is a small interfering RNA targeting β-adrenergic receptor 2, and is used to lower intraocular pressure
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Cat. No.: HY-117090
CAS No.: 362603-40-5
Synonyms: (rac)-4,5-DHP-AMT
Target:  

5-HT Receptor

Research Areas:  

Others

(rac)-AL-37350A ((rac)-4,5-DHP-AMT) is a 5-HT2 receptor agonist with intraocular pressure-lowering activity. (rac)-AL-37350A has high affinity and selectivity for the 5-HT2 receptor and effectively reduces intraocular pressure in conscious hypertensive cynomolgus monkeys.
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Cat. No.: HY-106332A
CAS No.: 119271-78-2
Synonyms: MK 417; (S)-MK-927
Target:  

Carbonic Anhydrase

Research Areas:  

Endocrinology

Sezolamide hydrochloride (MK 417) is a potent topical carbonic anhydrase inhibitor. Sezolamide hydrochloride can be used in studies to reduce intraocular pressure .
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Cat. No.: HY-108067
CAS No.: 581106-09-4
Target:  

Cannabinoid Receptor

Research Areas:  

Others

SAD448 is a CB1 and CB2 receptor agonist. SAD448 can lower intraocular pressure (IOP) .
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Cat. No.: HY-121600
CAS No.: 889860-85-9
Target:  

Cannabinoid Receptor

GAT229 is a CB1 positive allosteric modulator (PAM) that effectively reduces intraocular pressure (IOP) in high IOP mouse models and enhances CB1 receptor-mediated IOP-lowering effects. A 0.2% GAT229 solution or 10 mg/kg of GAT229 alone significantly reduces IOP. GAT229 is promising for research related to glaucoma and elevated intraocular pressure .
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Cat. No.: HY-106206
CAS No.: 170291-06-2
Research Areas:  

Cardiovascular Disease

AL-6598 is a partial agonist of the DP and EP prostaglandin receptors. AL-6598 reduces intraocular pressure and is used in glaucoma research .
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Cat. No.: HY-113797
CAS No.: 62435-92-1
Target:  

Adrenergic Receptor

Research Areas:  

Others

RS-52367 is a potent syntex β-adrenergic antagonist. RS-52367 decreases intraocular pressure with a mild systemic effect in dogs .
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Cat. No.: HY-113756
CAS No.: 903549-49-5
Research Areas:  

Others

trans-Latanoprost acid is an isomer of Latanoprost acid. trans-Latanoprost acid may have the activity of reducing intraocular pressure. trans-Latanoprost acid is mainly prepared as an analytical standard for impurity detection and quantification .
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Cat. No.: HY-160991
CAS No.: 83784-21-8
Synonyms: SP-204
Research Areas:  

Others Neurological Disease

Menabitan (SP-204) is an inhibitor for phosphodiesterase 9 (PDE 9), which acts as a non-opioid analgesic agent. Menabitan lowers the intraocular pressure in rabbit model .
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Cat. No.: HY-B0577S
Synonyms: PHXA41-d4
Latanoprost-d4 is the deuterium labeled Latanoprost. Latanoprost (PHXA41) is a prostaglandin F2α analogue and an agonist for the FP prostanoid receptor, and lowers intraocular-pressure (IOP).
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Cat. No.: HY-178233
CAS No.: 3032789-44-6
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

CAT335 is a TREK activator. CAT335 selectively and irreversibly activates TREK-1 CG∗. CAT335 can be used in the research of pain sensation, sleep, and intraocular pressure .
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Cat. No.: HY-B0397A
CAS No.: 76382-13-3
Synonyms: Diclofenamide disodium
Target:  

Carbonic Anhydrase

Research Areas:  

Neurological Disease

Dichlorphenamide (Diclofenamide) disodium is an orally active, specific, carbonic anhydrase inhibitor. Dichlorphenamide can reduce intraocular pressure by inhibiting the secretion of water from the eye. Dichlorphenamide can be used for glaucoma research .
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Cat. No.: HY-12720B
CAS No.: 73217-88-6
Synonyms: ALO 2145 dihydrochloride
Target:  

Adrenergic Receptor

Research Areas:  

Neurological Disease

Apraclonidine (ALO 2145) dihydrochloride, a selective α2 and weak α1 receptor agonist activity, effectively low intraocular pressure (IOP) in eyes. Apraclonidine dihydrochloride is a topical ophthalmic solution .
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Cat. No.: HY-B0577R
CAS No.: 130209-82-4
Synonyms: PHXA41 (Standard)
Research Areas:  

Others

Latanoprost (Standard) is the analytical standard of Latanoprost. This product is intended for research and analytical applications. Latanoprost (PHXA41) is a prostaglandin F2α analogue and an agonist for the FP prostanoid receptor, and lowers intraocular-pressure (IOP).
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Cat. No.: HY-160991A
CAS No.: 58019-50-4
Synonyms: SP-204 dihydrochloride
Research Areas:  

Others Neurological Disease

Menabitan dihydrochloride (SP-204 dihydrochloride) is the dihydrochloride form of Menabitan (HY-160991). Menabitan dihydrochloride is an inhibitor for phosphodiesterase 9 (PDE 9), which acts as a non-opioid analgesic agent. Menabitan dihydrochloride lowers the intraocular pressure in rabbit model .
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