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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
113 Results for "
MAD
" in MedChemExpress (MCE) Product Catalog:
Products (113)
113 Results for "MAD" in MCE Product Catalog:
Cat. No.: HY-RS27075
Target:
Research Areas:
Mad2l1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mad2l1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07950
Target:
Research Areas:
MAD2L1BP Human Pre-designed siRNA Set A contains three designed siRNAs for MAD2L1BP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22245
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Mxd1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mxd1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00666
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AMPD1 Human Pre-designed siRNA Set A contains three designed siRNAs for AMPD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08861
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MXD1 Human Pre-designed siRNA Set A contains three designed siRNAs for MXD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-13649R
CAS No.: 204205-90-3
Synonyms: ZIO 301 (Standard); D 24851 (Standard)
Research Areas:
Indibulin (Standard) is the analytical standard of Indibulin. This product is intended for research and analytical applications. Indibulin (ZIO 301), an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity. Indibulin reduces inter-kinetochoric tension, produces aberrant spindles, activates mitotic checkpoint proteins Mad2 and BubR1, and induces mitotic arrest and apoptosis .
Cat. No.: HY-174583
Human MEF2C mRNA encodes the human myocyte enhancer factor 2C (MEF2C) protein, a member of the MADS box transcription enhancer factor 2 (MEF2) family. MEF2C has both trans-activating and DNA binding activities and may play a role in maintaining the differentiated state of muscle cells.
Cat. No.: HY-123279
CAS No.: 292170-13-9
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OM137 is an aurora kinase inhibitor, with an IC50 of 21.7 μM (Aurora A kinase) and 2.4 μM (Aurora B kinase). OM137 also inhibits Cdk1/cyclinB and Cdk5/p25 with an approximate IC50 of 20 μM. OM137 reduces spindle checkpoint-signaling proteins (Mad2 and BubR1) at the kinetochores of chromosomes .
Cat. No.: HY-132162S
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7-MAD-MDCPT-d5 is the deuterated-labeled 7-MAD-MDCPT (HY-132162). 7-MAD-MDCPT, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs) .
Cat. No.: HY-179204S
CAS No.: 2911575-77-2
Cat. No.: HY-RS26284
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Research Areas:
Mad2l2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mad2l2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-183681S1
CAS No.: 3013694-23-7
Cat. No.: HY-164163
CAS No.: 2378428-24-9
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MP-PEG8-Val-Lys-Gly-7-MAD-MDCPT (example 4-3) is an ADC drug-linker conjugate composed of an payload 7-MAD-MDCPT (HY-132162) and a linker MP-PEG8-Val-Lys-Gly (HY-179261), used for synthesizing ADC .
Cat. No.: HY-171946
CAS No.: 2857037-73-9
Research Areas:
TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT is a drug-linker conjugate for ADC. TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT consists of a topoisomerase 1 inhibitor (Topi MF-6) (HY-175203) and a cleavable linker (Maleimide-Ph(3,5-F)-PEG4-Val-Ala) (HY-175218). TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT can be used for synthesis of ADCs .
Cat. No.: HY-P71536
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SMAD2; SMAD, Mothers Against DPP Homolog 2; Prev. MADH2; Mothers Against DPP Homolog 2; JV18-1; Mother Against DPP Homolog 2; MADR2; Mothers Against DPP Homolog; Mothers Against Decapentaplegic Homolog 2; MAD-Related Protein 2; MAD Homolog 2; SMAD Family
Species:
Human
Source:
E. coli
Cat. No.: HY-P83093
Synonyms: DKFZp781C1895; DKFZp781O1323; Dwfc; hSMAD 5; hSMAD5; JV5 1; JV5-1; MAD homolog 5; MAD mothers against decapentaplegic homolog 5; MAD; mothers against decapentaplegic homolog 5; MADH 5; MADH5; Mothers against decapentaplegic homolog 5; Mothers against DPP homolog 5; MusMLP; SMA and MAD related protein 5; SMAD 5; SMAD family member 5; SMAD mothers against DPP homolog 5; SMAD5; SMAD5; SMAD5_HUMAN.
Cat. No.: HY-P810361
Synonyms: Homolog of REV7 S cerevisiae, hREV7, MAD2 (mitotic arrest deficient yeast, homolog) like 2, MAD2 homolog, MAD2 like 2, MAD2 mitotic arrest deficient like 2, MAD2-like protein 2, MAD2B, MAD2l2, MD2L2_HUMAN
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
