203 Results for "

Sleep

" in MedChemExpress (MCE) Product Catalog:
Products (203)

203 Results for "Sleep" in MCE Product Catalog:

Cat. No.: HY-B1337R
CAS No.: 67-48-1
Choline chloride (Standard) is the analytical standard of Choline chloride (HY-B1337). This product is intended for research and analytical applications. Choline chloride is an orally active methylxanthine derivative. Choline chloride exhibits weak antihistaminic and anticholinergic activities and potentiates the effects of histamine and acetylcholine. Choline chloride relaxes bronchial smooth muscle, dilates coronary and peripheral blood vessels, increases urine output and electrolyte excretion, stimulates locomotor activity in the central nervous system, and induces transient hypotension following a pressor phase. Choline chloride modulates sleep architecture by increasing wakefulness time and reducing slow-wave sleep, without altering the frequency or severity of nocturnal hypoxemia, apnea, or hypopnea events. Choline chloride is used in studies of bronchospasm, nocturnal asthma, and chronic asthma .
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Cat. No.: HY-P1212
CAS No.: 193829-96-8
Synonyms: CST-14 (mouse, rat)
Target:  

Somatostatin Receptor

Research Areas:  

Neurological Disease

Cortistatin 14, mouse, rat (CST-14, human, rat), a neuropeptide with neuronal depressant and sleep modulating properties, can bind to all five cloned somatostatin receptors (SSTRs) and ghrelin receptor to exert its biological activities and co-exists with GABA within the cortex and hippocampus .
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Cat. No.: HY-P1501
CAS No.: 62568-57-4
Synonyms: Delta-Sleep Inducing Peptide
Target:  

SOD

Research Areas:  

Neurological Disease

δ-Sleep Inducing Peptide is a neuropeptide, with antioxidant and anxiolytic properties.
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Cat. No.: HY-P1501A
Synonyms: Delta-Sleep Inducing Peptide acetate
Target:  

SOD

Research Areas:  

Neurological Disease

δ-Sleep Inducing Peptide acetate is a neuropeptide, with antioxidant and anxiolytic properties .
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Cat. No.: HY-138014
CAS No.: 172986-25-3
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Cinazepam is a partial GABAA receptor agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders .
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Cat. No.: HY-W092533
CAS No.: 7730-20-3
Research Areas:  

Neurological Disease

6-Fluorotryptophan, a competitive inhibitor of tryptophan hydroxylase, produced a transient disruption of sleep in rats chronically implanted with EEG recording electrodes .
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Cat. No.: HY-W010155R
CAS No.: 526-55-6
Synonyms: Indole-3-ethanol (Standard)
Tryptophol (Standard) (Indole-3-ethanol (Standard)) is an analytical standard of Tryptophol (HY-W010155). This product is intended for use in research and analytical applications.Tryptophol is an aromatic alcohol and secondary metabolite produced by microorganisms. Tryptophol induces Apoptosis and cleavage of caspase-8. Tryptophol inhibits Cunninghamella blakesleeana biofilm. Tryptophol has anti-phage infection, biofilm formation regulation, anti-inflammatory, hemolytic, sleep induction, temperature change, seizure susceptibility and immune regulation activities. Tryptophol is used in the research of African trypanosomiasis, sleep disorders, epilepsy.
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Cat. No.: HY-W750342
CAS No.: 75238-45-8
Synonyms: Indole-3-ethanol-d4
Tryptophol-d4 (Indole-3-ethanol-d4) is the deuterium labeled Tryptophol (HY-W010155). Tryptophol is an aromatic alcohol and secondary metabolite produced by microorganisms. Tryptophol induces apoptosis and cleavage of caspase-8. Tryptophol inhibits Cunninghamella blakesleeana biofilm. Tryptophol has anti-phage infection, biofilm formation regulation, anti-inflammatory, hemolytic, sleep induction, temperature change, seizure susceptibility and immune regulation activities. Tryptophol is used in the research of African trypanosomiasis, sleep disorders, epilepsy .
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Cat. No.: HY-W004850
CAS No.: 7737-17-9
Aminoacetone hydrochloride is an α-aminoketone and also a catabolite of threonine and glycine. When accumulated under pathological conditions, Aminoacetone hydrochloride participates in oxidative damage and protein dysfunction via the production of reactive oxygen species (ROS) and methylglyoxal, and it is associated with phenotypes such as diabetes, mitochondrial damage and sleep disorders .
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Cat. No.: HY-106547
CAS No.: 99593-25-6
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Rilmazafone (450191S) is an orally active sleep inducer. Rilmazafone targets cytochrome P-450b and cytochrome P-450e. Rilmazafone induces hepatic drug-metabolizing enzyme activity in rats, mice and dogs. Rilmazafone is applicable for insomnia-related research .
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Cat. No.: HY-P4727
CAS No.: 82602-88-8
Synonyms: DSIP-isoD
Target:  

Inhibitory Antibodies

Research Areas:  

Others

(β-Asp5)-Delta-Sleep Inducing Peptide (DSIP-isoD) is a synthetic polypeptide that can be partially hydrolyzed by NaOH or SDS. (β-Asp5)-Delta-Sleep Inducing Peptide can be used to study the catalytic activity of mitochondrial protein L-isoaspartyl (D-aspartyl) methyltransferase (PIMT) .
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Cat. No.: HY-P1739
CAS No.: 69454-10-0
Target:  

Melanocortin Receptor

Research Areas:  

Neurological Disease

ACTH (34-39) is an adrenocorticotropic hormone fragment. ACTH (34-39) can be used in the study of stress-related sleep disorders .
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Cat. No.: HY-12301
CAS No.: 1224846-01-8
Purity:  98.83%
Research Areas:  

Neurological Disease

MK-3697 is an orally active orexin 2 receptor (OX2R) antagonist, with an IC50 value of 16 nM and a Ki value of 1.1 nM against human OX2R. MK-3697 blocks the wake-promoting OX2R signaling pathway, reduces active wake time, and increases slow-wave sleep and rapid eye movement sleep time in mice, rats and dogs. MK-3697 can be used for research on insomnia .
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Cat. No.: HY-150334
CAS No.: 50330-59-1
Target:  

Drug Metabolite

Research Areas:  

Neurological Disease

Rilmazolam is a metabolite of Rilmazafone (HY-106547) and hypnotic agent. Rilmazolam exerts a significant sleep-inducing effect. Rilmazolam can be used in insomnia-related research .
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Cat. No.: HY-101260
CAS No.: 1088991-95-0
Research Areas:  

Neurological Disease

DORA-22 is an orally active dual orexinergic receptor antagonist, and improves the sleep disruption and memory impairment. DORA-22 can be used for study of insomnia .
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Cat. No.: HY-W028389
CAS No.: 39243-02-2
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Pyrazolam is a brominated triazolo benzodiazepine psychoactive substance with oral effectiveness. Pyrazolam produces anxiolytic, sedative, and sleep-promoting effects. Pyrazolam can be used for the research of anxiety .
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Cat. No.: HY-129250
CAS No.: 1119807-02-1
Target:  

Histamine Receptor

Research Areas:  

Neurological Disease

AZD5213 is a selective and competitive human H3 receptor antagonist with a pKi value of 9.3 for hH3R. AZD5213 can be used for the research of sleep and cognitive regulation .
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Cat. No.: HY-116780A
CAS No.: 1225-65-6
Target:  

Cytochrome P450

Research Areas:  

Neurological Disease

Prothipendyl hydrochloride is a tricyclic azaphenothiazine neuroleptic agent. Prothipendyl hydrochloride is a substrate of the CYP isozymes CYP1A2, CYP2D6, CYP2C19 and CYP3A4. Prothipendyl hydrochloride has sedating and psychomotorically damping effects. Prothipendyl hydrochloride can be used for psychomotoric agitation, sleep disorder and anxiety research .
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Cat. No.: HY-116561
CAS No.: 19835-42-8
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

Adamantylmethamphetamine hydrochloride is a psychotic compound. Adamantylmethamphetamine hydrochloride has effects on hexobarbital sleeping time, spontaneous motor activity, and the potentiation of metrazole and antifatigue activity .
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Cat. No.: HY-177085
CAS No.: 2839408-03-4
Research Areas:  

Neurological Disease

Fumiporexant (Compound Example 93) is an orally active, brain-penetrant and selective Orexin receptor 2 (OX2R) antagonist. Fumiporexant regulates the sleep-wake cycle and emotion-related pathways in the central nervous system. Fumiporexant is promising for research of nervous system diseases such as insomnia and major depressive disorder .
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