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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
168 Results for "
circulates
" in MedChemExpress (MCE) Product Catalog:
Products (168)
168 Results for "circulates" in MCE Product Catalog:
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Cat. No.: HY-177440
CAS No.: 958860-12-3
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T26A is a highly selective prostaglandin transporter (PGT) inhibitor.T26A does not interact with the PGT homolog OATPc, blocks PGT-mediated PGE2 influx, and blocks PGE2 metabolism.T26A retains PGE2 in the extracellular compartment and reduces intracellular PGE2 metabolites.T26A elevates circulating endogenous PGE2 levels, reduces circulating endogenous PGE2 metabolite levels, and slows metabolism of exogenously injected PGE2 in Rattus norvegicus via intravenous injection.T26A does not affect PGE2 synthesis.T26A can be used for the research of PGT function in adult animals .
Cat. No.: HY-P99443
CAS No.: 395639-53-9
Synonyms: HuDreg-55
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Cat. No.: HY-163480
CAS No.: 2796997-12-9
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Cat. No.: HY-46749
CAS No.: 2565656-71-3
Synonyms: LY3473329 tetrahydrochloride
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Muvalaplin tetrahydrochloride (LY3473329 tetrahydrochloride) is an orally active small molecule apolipoprotein a (apolipoprotein a) inhibitor that binds to the KIV8 domain (Kd = 22 nM) and kringle IV domains 7 and 8, blocks the non-covalent interaction between apo (a) and apoB-100, and prevents Lp (a) assembly, thereby lowering circulating Lp (a) levels. Muvalaplin tetrahydrochloride can be used in research on atherosclerotic cardiovascular disease .
Cat. No.: HY-125053A
Purity: 99.58%
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Cat. No.: HY-124863A
CAS No.: 241476-71-1
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(R)-AAL is an immunomodulator. (R)-AAL decreases circulating T lymphocytes in rats, with an ID50 value of 0.009 mg/kg. (R)-AAL is a substrate of sphingosine kinase (SphK), which catalyzes the phosphorylation of (R)-AAL .
Cat. No.: HY-P99645
CAS No.: 2416984-26-2
Synonyms: RPH 104
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Cat. No.: HY-P99790
CAS No.: 147191-91-1
Synonyms: CEN 000029; cM-T412
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Cat. No.: HY-153485
CAS No.: 2131025-82-4
Synonyms: ISIS 766720; IONIS-GHR-LRx
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Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.
Cat. No.: HY-70002AS
CAS No.: 2748567-63-5
Synonyms: N-Desmethyl MDV 3100-d6
Cat. No.: HY-P1573
CAS No.: 123337-89-3
Synonyms: BNP-45, rat
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Cat. No.: HY-P991660
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Cat. No.: HY-P4063
CAS No.: 1350661-05-0
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Synonyms: Mebeverine metabolite Mebeverine acid
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Mebeverine acid (Mebeverine metabolite Mebeverine acid) is a secondary metabolite of the intestinal antispasmodic agent Mebeverine (HY-A0078). Mebeverine acid is generated by the hydrolysis of Mebeverine in the body and is considered a key circulating metabolite. Mebeverine acid is an important marker for oral Mebeverine .
Cat. No.: HY-19771
CAS No.: 1819986-22-5
Synonyms: GSK294; amyloid P-IN-1
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GSK3039294 is an orally active pro-drug of Miridesap (HY-101861), a circulating serum amyloid P component depleter. GSK3039294 undergoes hydrolysis to form miridesap via a monoester intermediate. GSK3039294 can be used for the research of systemic amyloidosis .
Cat. No.: HY-153485A
CAS No.: 2131025-83-5
Synonyms: ISIS 766720 sodium; IONIS-GHR-LRx sodium
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Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.
Cat. No.: HY-P99608
CAS No.: 569658-80-6
Cat. No.: HY-100652A
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O-Desmethyl apixaban sulfate sodium is the major circulating metabolite of Apixaban (HY-50667) in humans. O-Desmethyl apixaban sulfate sodium exhibits no inhibitory activity against human activated factor X (FXa), with a Ki > 20 μM .
Cat. No.: HY-158093
CAS No.: 2409826-23-7
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NIC-12 is a potent NLRP3 inhibitor. NIC-12 selectively reduces circulating IL-1ß levels in the LPS-endotoxemia mice model. NIC-12 inhibits NLRP3 inflammasome activation in mouse macrophages .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
