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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
168 Results for "
circulates
" in MedChemExpress (MCE) Product Catalog:
Products (168)
168 Results for "circulates" in MCE Product Catalog:
Cat. No.: HY-150254
CAS No.: 2999629-17-1
Target:
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SLB1122168 is a Spinster Homolog 2 (Spns2) inhibitor. SLB1122168 inhibits Spns2-mediated sphingosine-1-phosphate (S1P) release with an IC50 of 94 nM. SLB1122168 induces lymphopenia in circulating lymphocytes in mice and rats .
Cat. No.: HY-12769S1
Purity: ≥99.0%
Synonyms: Mebeverine metabolite Mebeverine acid-d5 hydrochloride
Cat. No.: HY-145542R
CAS No.: 139144-12-0
Cat. No.: HY-19020
CAS No.: 94936-90-0
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FK-664 is a leukotriene inhibitor. FK-664 enhances ventricular contractility and shortens the time to peak tension in cardiac cells. FK-664 reduces mean circulating pressure (MCP) in a canine model of heart failure. FK-664 can be used in research on cardiovascular diseases such as heart failure .
Cat. No.: HY-W747868
CAS No.: 1375799-59-9
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Molidustat sodium is an orally active inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) with IC50 values of 480 nM, 280 nM, and 450 nM for PHD1, PHD2, and PHD3, respectively. Molidustat sodium can elevate the levels of circulating erythropoietin (EPO) to near-normal physiological ranges. Molidustat sodium can be utilized in the research of renal anemia .
Cat. No.: HY-P11083
CAS No.: 1352335-71-7
Cat. No.: HY-W440831
DSPE-PEG1000-azide is a phospholipid with covalently attached polydisperse PEG. This polymer is commonly used for the preparation of long circulating liposomes. The azide moiety is reactive with alkyne to form a stable triazole bond.
Cat. No.: HY-P1573A
Synonyms: BNP-45, rat TFA
Research Areas:
Cat. No.: HY-W401407
CAS No.: 152503-50-9
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Diosmetin-3-O-glucuronide is a major circulating metabolite of Diosmetin (HY-N0125) in plasma and in urine. Diosmetin is a natural flavonoid which inhibits human CYP1A enzyme activity .
Cat. No.: HY-119064
CAS No.: 85493-98-7
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L-645164 is a potent inhibitor of hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase. L-645164 produces substantial decreases in circulating serum cholesterol concentrations in dogs. L-645164 is promising for research of central nervous system disorders .
Cat. No.: HY-125053
CAS No.: 710312-77-9
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Cat. No.: HY-126044
CAS No.: 368451-07-4
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6-Hydroxy bexarotene is the main circulating metabolite of bexarotene, found in rats, dogs, and humans. Compared to the parent compound, 6-hydroxy-bexarotene shows a significantly reduced ability to bind to retinoid receptors and exhibits very minimal activity in activating retinoic acid receptors .
Cat. No.: HY-162655A
CAS No.: 2764877-62-3
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SLF80821178 hydrochloride is an orally active inhibitor for sphingosine-1-phosphate transporter (Spns2), that inhibits the sphingosine-1-phosphate (S1P) release in HeLa with an IC50 of 51 nM. SLF80821178 hydrochloride reduces the circulating lymphocyte without affecting plasma S1P levels in mice .
Cat. No.: HY-113221AS
Cat. No.: HY-145542S
CAS No.: 1334532-23-8
Cat. No.: HY-124099
CAS No.: 110545-79-4
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SCH 40120 is a potent leukotriene inhibitor with antiinflammatory effects. SCH 40120 suppresses T cell proliferative responses, antigen-specific and poly-clonally-induced in vitro antibody responses. SCH 40120 suppresses an edematous response and inhibits the recruitment of circulating neutrophils into sites of inflammation. SCH 40120 is proming for rasearch of anti-psoriatic agents .
Cat. No.: HY-12769R
CAS No.: 475203-77-1
Synonyms: Mebeverine metabolite Mebeverine acid (Standard)
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Mebeverine acid (Mebeverine metabolite Mebeverine acid) (Standard) is the analytical standard for Mebeverine acid (HY-12769). This product is used for research and analytical applications. Mebeverine acid is a secondary metabolite of the intestinal antispasmodic Mebeverine (HY-A0078). Mebeverine acid is generated by the hydrolysis of Mebeverine in the body and is considered a key circulating metabolite. Mebeverine acid is an important marker of oral Mebeverine.
Cat. No.: HY-12769S
CAS No.: 2070015-30-2
Synonyms: Mebeverine metabolite Mebeverine acid-d5
Cat. No.: HY-165393
CAS No.: 945009-57-4
Synonyms: N-(9E)-9-Octadecen-1-ylsulfamide
Target:
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Elaidyl-sulfamide (N-(9E)-9-Octadecen-1-ylsulfamide) is a PPARα agonist. Elaidyl-sulfamide reduces body weight gain and food intake and reduces circulating cholesterol levels and increases both glucose and insulin levels. Elaidyl-sulfamide has the potential for the research of complicated obesity .
Cat. No.: HY-70002AR
CAS No.: 1242137-16-1
Synonyms: N-Desmethyl MDV 3100 (Standard)
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N-desmethyl Enzalutamide (Standard) is the analytical standard of N-desmethyl Enzalutamide. This product is intended for research and analytical applications. N-desmethyl Enzalutamide is the active metabolite of Enzalutamide.N-desmethyl Enzalutamide is the active metabolite of Enzalutamide. N-desmethyl Enzalutamide demonstrates primary and secondary pharmacodynamics of similar potency to Enzalutamide and circulates at approximately the same plasma concentrations as enzalutamide .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
