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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
598 Results for "
regulators
" in MedChemExpress (MCE) Product Catalog:
Products (598)
598 Results for "regulators" in MCE Product Catalog:
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2 Cited Publications
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CCG-50014 is the most potent against the regulator of G-protein signaling protein type 4 (RGS4) (IC50 =30 nM) and is >20-fold selective for RGS4 over other RGS proteins. CCG-50014 binds covalently to the RGS, forming an adduct on two cysteine residues located in an allosteric regulatory site . CCG50014, reduces nociceptive responses and enhances opioid-mediated analgesic effects in the mouse formalin test .
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2 Cited Publications
Synonyms: O-Acetyl-L-carnitine; ALCAR
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2 Cited Publications
Synonyms: O-Acetyl-L-carnitine hydrochloride; ALCAR hydrochloride
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2 Cited Publications
Cat. No.: HY-P1925A
CAS No.: 1222186-26-6
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1 Cited Publications
Synonyms: BMS-214778; VEC-162
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Tasimelteon (BMS-214778) is an orally active and selective dual melatonin receptor agonist (DMRA). Tasimelteon has 2.1-4.4 times greater affinity for the MT2 receptor than for the MT1 receptor. Tasimelteon is a circadian regulator and has the potential for Non-24-Hour Sleep-Wake Disorder (Non-24) .
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CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 (OC2, a master regulator of androgen receptor) with a Kd of 7.43 uM in SPR assays, binding to OC2-HOX domain directly. CSRM617 hydrochloride induces apoptosis by appearance of cleaved Caspase-3 and PARP. CSRM617 hydrochloride is well tolerated in the prostate cancer mouse model
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1 Cited Publications
Cat. No.: HY-W131845
CAS No.: 16672-87-0
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1 Cited Publications
Cat. No.: HY-N8241
CAS No.: 103188-48-3
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(R)-Vanzacaftor ((R)-VX-121) is a Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) modulator with max activity of 30-60% and EC50 <1 μM in enteroid cells. (R)-Vanzacaftor can be used for the research of cystic fibrosis .
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1 Cited Publications
Cat. No.: HY-W011151
CAS No.: 6025-53-2
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Plants Cytokinin Catharanthus roseus (L.) G. Don Agricultural Research Apocynaceae Alkaloids Other Alkaloids Other Diseases Phytohormone Disease Research Fields
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1 Cited Publications
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1 Cited Publications
Synonyms: GLPG 3067; ABBV-3067
Navocaftor (GLPG 3067), as a cystic fibrosis transmembrane regulator (CFTR), is a protein modulator (US 20200377491 Al, example 1) .
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1 Cited Publications
Cat. No.: HY-W014240
CAS No.: 101-21-3
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Chlorpropham is a carbamate herbicide and plant growth regulator. Chlorpropham inhibits mitosis and cell division by interfering with the organisation of the spindle microtubules .
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1 Cited Publications
Synonyms: PTI-801 sodium
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Posenacaftor (PTI-801) sodium is a cystic fibrosis transmembrane regulator (CFTR) protein modulator that corrects the folding and trafficking of CFTR protein. Posenacaftor sodium is used for the research of cystic fibrosis (CF) .
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1 Cited Publications
Synonyms: ABBV-2222; GLPG-2222
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Galicaftor (ABBV-2222; GLPG-2222) is a potent and orally active cystic fibrosis transmembrane conductance regulator (CFTR) corrector. Galicaftor can be used for cystic fibrosis research .
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Podocarpus nakaii Hayata Other Diseases Plants Podocarpaceae Disease Research Fields Steroids
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
