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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
79 Results for "
OATPs
" in MedChemExpress (MCE) Product Catalog:
Products (79)
79 Results for "OATPs" in MCE Product Catalog:
Cat. No.: HY-108347A
CAS No.: 142716-85-6
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CP-100356 is an orally active dual MDR1 (P-gp)/BCRP inhibitor, with an IC50s of 0.5 and 1.5 µM for inhibiting MDR1-mediated Calcein-AM transport and BCRP-mediated Prazosin transport, respectively. CP-100356 is also a weak inhibitor of OATP1B1 (IC50 = ∼66 µM). CP-100356 is devoid of inhibition against MRP2 and major human P450 enzymes (IC50 > 15 µM) .
Cat. No.: HY-113293BS
CAS No.: 2734919-86-7
Cat. No.: HY-B0396A
CAS No.: 211558-19-9
Synonyms: L084 hydrochloride
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Tebipenem pivoxil hydrochloride (L084 hydrochloride) is an orally active carbapenem Antibiotic. Tebipenem pivoxil hydrochloride acts as a substrate of OATP1A2 with high affinity for this transporter (Km = 41.1 μM) . Tebipenem pivoxil hydrochloride achieves intestinal absorption via carrier-mediated uptake and simple diffusion. Tebipenem pivoxil hydrochloride inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, multidrug-resistant bacteria, and pathogens producing extended-spectrum β-lactamases. Tebipenem pivoxil hydrochloride eliminates intestinal infection pathogens and reduces mortality in septic mice. Tebipenem pivoxil hydrochloride can be used in research related to bacterial pneumonia, severe gastrointestinal infections, bacterial sepsis, complicated urinary tract infections, and acute pyelonephritis .
Cat. No.: HY-N8497
CAS No.: 105350-54-7
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Cat. No.: HY-138142
CAS No.: 13879-04-4
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Triterpenes Terpenoids Metabolic Disease Plants Other Families Extract Disease Research Fields
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Cat. No.: HY-N3513R
CAS No.: 62949-79-5
Synonyms: Kuwanon C (Standard)
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Cat. No.: HY-119695AR
CAS No.: 139893-43-9
Synonyms: Tenivastatin ammonium (Standard)
Synonyms: Piperazine estrone sulfate (Standard); Estrone sulfate piperazine salt (Standard)
Category:
Cat. No.: HY-119695AS
Synonyms: Tenivastatin-d6 ammonium
Cat. No.: HY-119695AS1
Synonyms: Tenivastatin-d9 ammonium
Cat. No.: HY-119695S
CAS No.: 2747915-75-7
Synonyms: Tenivastatin-d6
Cat. No.: HY-10466S
CAS No.: 1801709-41-0
Synonyms: BMS-790052-d6; EBP 883-d6
Cat. No.: HY-10466S2
Synonyms: BMS-790052-d16; EBP 883-d16
Cat. No.: HY-10466R
CAS No.: 1009119-64-5
Synonyms: BMS-790052 (Standard); EBP 883 (Standard)
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Daclatasvir (Standard) is the analytical standard of Daclatasvir. This product is intended for research and analytical applications. Daclatasvir (BMS-790052) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 µM and 3.27 µM, respectively .
Cat. No.: HY-16278A
CAS No.: 956136-98-4
Synonyms: LCQ 908 sodium
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Pradigastat sodium (LCQ 908 sodium) is a selective and orally effective diacylglyceryl acyltransferase 1 (DGAT1) inhibitor with IC50 at 0.157 µM. Pradigastat is primarily used to study diseases associated with abnormal triglyceride metabolism. Pradigastat has anti-obesity and anti-diabetic effects. Pradigastat inhibited BCRP, OATP1B1, OATP1B3 and OAT3 activities with IC50 of 5 µM, 1.66µM, 3.34µM and 0.973µM, respectively. In addition, Pradigastat has antiviral activity and can inhibit hepatitis C virus replication in vitro .
Cat. No.: HY-10466S1
Synonyms: BMS-790052-13C2,d6; EBP 883-13C2,d6
Cat. No.: HY-W002438R
CAS No.: 2380-86-1
Cat. No.: HY-W011819R
CAS No.: 821-38-5
Cat. No.: HY-N15726
CAS No.: 2414481-40-4
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Caesalpiniaceae Extract Cassia obtusifolia (L.) H. S. Irwin & Barneby Plants Saccharides Monosaccharides
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
